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当前位置: 首页 > 产品中心 > Other_reagents > Adipogen/Arglabin/AG-CN2-0458-M005/5 mg
商品详细Adipogen/Arglabin/AG-CN2-0458-M005/5 mg
Adipogen/Arglabin/AG-CN2-0458-M005/5 mg
Adipogen/Arglabin/AG-CN2-0458-M005/5 mg
商品编号: AG-CN2-0458-M005
品牌: Adipogen Inc
市场价: ¥6000.00
美元价: 3600.00
产地: 美国(厂家直采)
公司:
产品分类: 其他试剂
公司分类: Other_reagents
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
MoreInformation
ProductDetails
SynonymsArglABIne
ProductTypeChemical
Properties
FormulaC15H18O3
MW246.3
CAS84692-91-1
Source/HostChemicalsSemi-syntheticfromparthenolide(AG-CN2-0455),whichisisolatedfromMagnoliagrandiflora.
PurityChemicals≥98%(HPLC)
AppearanceWhitetooff-whitesolid.
SolubilitySolubleindryDMSO,100%ethanolormethanol.Insolubleinwater.
InChiKeyUVJYAKBJSGRTHA-CUZKYEQNSA-N
ShippingandHandling
ShippingAMBIENT
ShortTermStorage+4°C
LongTermStorage-20°C
HandlingAdviceProtectfromlight.
Use/StabilityStableforatleast2yearsafterreceiptwhenstoredat-20°C.
Documents
MSDSDownloadPDF
ProductSpecificationSheet
DatasheetDownloadPDF
  • Anticancercompound.
  • Farnesyltransferaseinhibitor.
  • Potentanti-inflammatoryagent.
  • NF-κBinhibitor.
  • Inflammasomeinhibitor.
  • Antiatherogenic.Preventstheaccumulationoflipidcontainingplaquesinarteries.
ProductReferences
  1. InvitroBIOLOGicalactivitiesofarglabin,asesquiterpenelactonefromtheChineseherbArtemisiamyrianthaWall:C.Bottex-Gauthier,etal.;Biotechnol.Ther.4,77(1993)
  2. Arglabin-DMA,aplantderivedsesquiterpene,inhibitsfarnesyltransferase:T.E.Shaikenov,etal.;Oncol.Rep.8,173(2001)
  3. Biomimeticsemisynthesisofarglabinfromparthenolide:J.D.Zhai,etal.;JOC77,7103(2012)
  4. Synthesisandbiologicalevaluationofantitumor-activearglabinderivatives:R.Csuk,etal.;ArchPharm.345,215(2012)
  5. Sesquiterpenelactonesandtheirderivativesinhibithighglucose-inducedNF-κBactivationandMCP-1andTGF-β1expressioninratmesangialcells:Q.Q.Jia,etal.;Molecules18,13061(2013)
  6. Hemisynthesisofanaturallyoccurringclinicallysignificantantitumorarglabinfromludartin:S.H.Lone&K.A.Bhat;THL56,1908(2015)
  7. Anti-InflammatoryandantiatherogeniceffectsoftheNLRP3InflammasomeinhibitorArglabininApoE2.Kimicefedahigh-fatdiet:A.ABDerrazak,etal.;Circulation131,1061(2015)
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。