脂肪原/抗血小板。二氢氯化物/AG-CP3-7002-M005/5 mg
商品编号：
AG-CP3-7002-M005
品牌：
Adipogen Inc
市场价：
¥800.00
美元价：
480.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | [(S)-1-Carboxy-2-phenylethyl]-carbamoyl-Arg-Val-arginal.2HCl |
| ProductType | Chemical |
| Properties | |
| Formula | C27H44N10O6.2HCl |
| MW | 604.7.72.9 |
| CAS | 37682-72-7 |
| RTECS | YV9350800 |
| Source/HostChemicals | Synthetic. |
| PurityChemicals | ≥97%(HPLC) |
| Appearance | Whitetooff-whitesolid. |
| Solubility | Solubleinwater,ethanol,methanol,DMSOoracetonitrile. |
| BIOLOGicalActivity | InhibitoryActivity:≥30U/mg(Trypsin,L-BAPA) |
| InChiKey | YAHXZYICKJUJEO-BXLPLHKWSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Protectfromlightandmoisture. |
| Use/StABIlity | Stableforatleast3yearsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- PotentreversIBLeinhibitorofserine/cysteineproteasesandsometrypsin-likeproteases.Inhibitspapain,trypsinandtrypsin-likeserineproteasesaswellascathepsinA,BandD.
- Similaractivityspectrumcomparabletoleupeptin(AG-CP3-7000).
- Actsbyformingahemiacetaladductbetweenitsaldehydegroupandtheactiveserineoftheproteinase.
- InhibitstransformationofNIH3T3cellsaftertransfectionwithanactivatedH-rasoncogene.
- Usedtoevaluatetheroleofproteasesintheprocessofmalignantcelltransformations.
- Showsantibacterialandantiparasiticactivity.
ProductReferences
- Antipain,anewproteaseinhibitorisolatedfromactinomycetes:H.Suda,etal.;J.Antibiot.25,263(1972)
- Structuresandactivitiesofproteaseinhibitorsofmicrobialorigin:H.Umezawa;MethodsEnzymol.45,678(1976)
- Inhibitionofproteolyticactivityofcalciumactivatedneutralproteasebyleupeptinandantipain:T.Toyo-Oka,etal.;BBRC82,484(1978)
- Effectsofantipain(aproteaseinhibitor)onrespiration,viability,andexcisionofpyrimidinedimersinUV-irrADIatedEscherichiacolicells:P.A.Swenson&R.L.Schenley;J.Bacteriol.135,1167(1978)
- EffectofCa2+ontheinhibitionofcalcium-activatedneutralproteasebyleupeptin,antipainandepoxysuccinatederivatives:K.Suzuki,etal.;FEBSLett.136,119(1981)
- InhibitionofLeishmaniaamastigotegrowthbyantipainandleupeptin:G.H.Coombs&J.Baxter;Ann.Trop.Med.Parasitol.78,21(1984)
- Antipainorleupeptinincombinationwithaspirinorindomethacinsynergisticallyinhibithumanplateletactivationbythrombinandtrypsin:M.Ruggiero&E.G.Lapetina;Adv.ProstaglandinThromboxaneLeukot.Res.17A,563(1987)
- InhibitionofH-rasoncogenetransformationofNIH3T3cellsbyproteaseinhibitors:S.J.Garte,etal.;CancerRes.47,3159(1987)
- Reversibleconversionoftyrosinehydroxylasetoaninactiveformbyantipain:S.Okuno&H.Fujisawa;BBRC146,1375(1987)
- Antipain-inducedsuppressionofoncogeneexpressioninH-ras-transformedNIH3T3cells:L.R.Cox,etal.;CancerRes.51,4810(1991)
- Effectsoftheproteaseinhibitorantipainoncellmalignanttransformation:M.Vaccari,etal.;AnticancerRes.19,589(1999)
- Lysosomes,growthfactoractivity,andcarcinogenicimplications:M.Melzer;Crit.Rev.Eukaryot.Gene.Expr.22,345(2012)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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