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当前位置: 首页 > 产品中心 > Other_reagents > Adipogen/Antibiotic UK-1/BVT-0013-M001/1 mg
商品详细Adipogen/Antibiotic UK-1/BVT-0013-M001/1 mg
Adipogen/Antibiotic UK-1/BVT-0013-M001/1 mg
Adipogen/Antibiotic UK-1/BVT-0013-M001/1 mg
商品编号: BVT-0013-M001
品牌: Adipogen Inc
市场价: ¥4800.00
美元价: 2880.00
产地: 美国(厂家直采)
公司:
产品分类: 其他试剂
公司分类: Other_reagents
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
MoreInformation
ProductDetails
SynonymsUK1;Methyl2"-(2-hydroxyphenyl)-[2,4"-bibenzo[d]oxazole]-4-carboxylate;2"-(2-Hydroxyphenyl)-(2,4"-bibenzoxazole)-4-carboxylicacidmethylester
ProductTypeChemical
Properties
FormulaC22H14N2O5
MW386.4
CAS151271-53-3
Source/HostChemicalsIsolatedfromStreptomycessp.K17/9.
PurityChemicals≥98%(HPLC)
AppearanceWhitetooff-whitesolid.
SolubilitySolubleinDMSO,acetoneordimethylformamide.
IdentityDeterminedby1H-NMR.
DeclarationManufacturedbyBioViotica.
InChiKeyNGKIDJMAXLRJRL-UHFFFAOYSA-N
ShippingandHandling
ShippingAMBIENT
ShortTermStorage+4°C
LongTermStorage-20°C
Use/StABIlityStableforatleast1yearafterreceiptwhenstoredat-20°C.
Afterreconstitutionprotectfromlightat-20°C.
Documents
MSDSDownloadPDF
ProductSpecificationSheet
DatasheetDownloadPDF
  • Antibiotic.
  • Antifungal.
  • TopoisomeraseII(TopoII)inhibitor.Mg2+-andZn2+-dependentDNAbindingagent.
  • Potentanticancercompound.
ProductReferences
  1. UK-1,anovelcytotoxicmetabolitefromStreptomycessp.517-02.I.Taxonomy,fermentation,isolation,physico-chemicalandBIOLOGicalproperties:M.Ueki,etal.;J.Antibiot.46,1089(1993)
  2. UK-1,anovelcytotoxicmetabolitefromStreptomycessp.517-02.II.Structuralelucidation:K.Shibata,etal.;J.Antibiot.46,1095(1993)
  3. UK-1,anovelcytotoxicmetabolitefromStreptomycessp.517-02.III.AntibacterialactionofdemethylUK-1:M.UekiandM.Taniguchi;J.Antibiot.50,788(1997)
  4. UK-1,anovelcytotoxicmetabolitefromStreptomycessp.517-02.IV.AntifungalactionofmethylUK-1:M.Ueki,etal.;J.Antibiot.51,883(1998)
  5. Thenovelbis(benzoxazole)cytotoxicnaturalproductUK-1isamagnesiumion-dependentDNAbindingagentandinhibitorofhumantopoisomeraseII:M.B.Reynolds,etal.;Bioorg.Chem.27,326(1999)
  6. Evaluationofcomplexationofmetal-mediatedDNA-bindingdrugstooligonucleotidesviaelectrosprayionizationmassspectrometry:M.L.Reyzer,etal.;Nucl.AcidsRes.29,E103(2001)
  7. SynthesisandevaluationofanticancerbenzoxazolesandbenzimidazolesrelatedtoUK-1:D.Kumar,etal.;Bioorg.Med.Chem.10,3997(2002)
  8. CriticalstructuralmotifforthecatalyticinhibitionofhumantopoisomeraseIIbyUK-1andanalogs:B.B.Wang,etal.;Bioorg.Med.Chem.Lett.14,3221(2004)
  9. Synthesisandantimicrobialactivityofsome5-[2-(morpholin-4-yl)acetamido]and/or5-[2-(4-substitutedpiperazin-1-yl)acetamido]-2-(p-substitutedphenyl)benzoxazoles:O.Temiz-Arpaci,etal.;Arch.Pharm.338,105(2005)
  10. Synthesisandanticancerevaluationofbis(benzimidazoles),bis(benzoxazoles),andbenzothiazoles:S.T.Huang,etal.;Bioorg.Med.Chem.14,6106(2006)
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。