脂肪原/蒽林/CDX-D0308-G005/5 g
商品编号：
CDX-D0308-G005
品牌：
Adipogen Inc
市场价：
¥5640.00
美元价：
3384.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | Dithranol;1,8-Dihydroxyanthrone;Anthracene-1,8,9-triol;NSC43970;NSC629313 |
| ProductType | Chemical |
| Properties | |
| Formula | C14H10O3 |
| MW | 226.2 |
| CAS | 1143-38-0 |
| RTECS | CB8927000 |
| Source/HostChemicals | Synthetic. |
| PurityChemicals | ≥98%(HPLC) |
| Appearance | Faintyellowtoyellowpowder. |
| Solubility | Solubleinacetone. |
| Identity | DeterminedbyNMR. |
| Declaration | ManufacturedbyChemodex. |
| OtherProductData | ClickhereforOriginalManufacturerProductDatasheet Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet. |
| InChiKey | NUZWLKWWNNJHPT-UHFFFAOYSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Keepcoolanddry. Protectfromlightandmoisture. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
Anthralinisaleukotrienebiosynthesisinhibitor.ItinhibitsLTB4ω-oxidationanddisruptsmitochondriafunction.Anthralinisusedinthetreatmentofpsoriasis,asafungicide,inthetreatmentofringworminfectionsandinchronicdermatoses.Itaccumulatesinmitochondriawhereitinterfereswiththesupplyofenergytothecell,probablybytheoxidationofdithranolreleasingfreerADIcals.ThisimpedesDNAreplicationandsoslowstheexcessivecelldivisionthatoccursinpsoriaticplaques.Numerousstudieshavedemonstratedanti-proliferativeandanti-inflammatoryeffectsofanthralinonpsoriaticandnormalskin.ItisalsousedasmatrixsubstanceforMALDI-MS(matrix-assistedlaserdesorptionionizationMS).
ProductReferences
(1)R.E.Ashton,etal.;J.Am.Acad.Dermatol.9,173(1983)|(2)J.M.Schröder;J.Invest.Dermatol.87,624(1986)|(3)C.E.Orfanos,etal.;Drugs34,459(1987)(Review)|(4)L.Kemeny,etal.;SkinPharmacol.3,1(1990)|(5)K.Müller;Biochem.Pharmacol.53,1215(1997)(Review)|(6)K.Pavithran;IndianJ.Dermatol.Venereol.Leprol.67,104(2001)|(7)C.H.Le,etal.;Anal.Chem.84,8391(2012)|(8)C.Ronpirin&T.Tencomnao;Genet.Mol.Res.11,412(2012)|(9)S.E.George,etal.;J.Pharm.Pharmacol.65,552(2013)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
联络我们
