Integrin is a heterodimeric cell-surface receptor and combined with RGD (arginine-glycine-aspartate) sequence exposed to outside to mediate adhesion and fixation between cells and matrix of outside of cells. In addition, while integrin involved in cell signaling and gene expression related to growth, movement, and survival of cells, integrin is also used as a marker for disease research as its abnormal regulation links to blood coagulation, inflammatory response and cancer expression.AngioFlamma® 749 of BioActs is a fluorescent targeted probe that is applied with fluorescence technique of Flamma® 749 based on  RGD peptide, and it is used as a probe for in vivo detection of inflammatory response, tumor and angiogenesis. Excitation ? Emission (nm): 749 / 774 nm.