Adipogen/Anacardic acid/AG-CR1-0046-M025/25 mg
商品编号：
AG-CR1-0046-M025
品牌：
Adipogen Inc
市场价：
¥3100.00
美元价：
1860.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | 2-Hydroxy-6-pentadecylbenzoicacid;6-Pentadecylsalicylicacid;AA |
| ProductType | Chemical |
| Properties | |
| Formula | C22H36O3 |
| MW | 348.5 |
| MerckIndex | 14:621 |
| CAS | 16611-84-0 |
| PurityChemicals | ≥98%(HPLC) |
| Appearance | Whitetooff-whitesolid. |
| Solubility | Solublein100%ethanol,methanol,DMSO,dichloromethaneorethylacetate. |
| OtherProductData | Stocksolutionsarestableforupto3monthswhenstoredat-20°C. |
| InChiKey | ADFWQBGTDJIESE-UHFFFAOYSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | +4°C |
| HandlingAdvice | Afterreconstitution,preparealiquotsandstoreat-20°C. Protectfromlight. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat+4°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Potenthistoneacetyltransferase(HAT)inhibitor[1,2].
- Antibacterial[3].
- SUMOylationinhibitor[4].
- Lipoxygenaseinhibitor[5].
- NF-κBinhibitor[6].
- Anti-tumorcompound[2,6-8].
- Anti-inflammatory[6].
- Apoptosisinducer[6,7].
- Antiproliferative[7].
ProductReferences
- Smallmoleculemodulatorsofhistoneacetyltransferasep300:K.Balasubramanyam,etal.;J.Biol.Chem.278,19134(2003)
- InhibitionofhistoneacetyltransferaseactivitybyanacardicacidsensitizestumorcellstoionizingrADIation:Y.Sun,etal.;FEBSLett. 580,4353(2006)
- Antibacterialactivityofanacardicacidandtotarol,aloneandincombinationwithmethicillin,againstmethicillin-resistantStaphylococcusaureus:H.Muroi&I.Kubo;J.Appl.Bacteriol.80,387(1996)
- GinkgolicacidinhibitsproteinSUMOylationbyblockingformationoftheE1-SUMOintermediate:I.Fukuda,etal.;Chem.Biol. 16,133(2009)
- Inhibitionoflipoxygenaseandprostaglandinendoperoxidesynthasebyanacardicacids:R.Grazzini,etal.;BBRC176,775(1991)
- Anacardicacid(6-nonadecylsalicylicacid),aninhibitorofhistoneacetyltransferase,suppressesexpressionofnuclearfactor-kappaB-regulatedgeneproductsinvolvedincellsurvival,proliferation,invasion,andinflammationthroughinhibitionoftheinhibitorysubunitofnuclearfactor-kappaBalphakinase,leadingtopotentiationofapoptosis:B.Sung,etal.;Blood111,4880(2008)
- Anacardicacidinducescaspase-independentapoptosisandradiosensitizespituitaryadenomacells:S.Sukumari-Ramesh,etal.;J.Neurosurg.114,1681(2011)
- Anacardicacidinhibitsestrogenreceptoralpha-DNAbindingandreducestargetgenetranscriptionandbreastcancercellproliferation:D.J.Schultz,etal.;Mol.CancerTher.9,594(2010)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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