Adipogen/Amorfrutin A/AG-CN2-0462-C500/500 µg
商品编号：
AG-CN2-0462-C500
品牌：
Adipogen Inc
市场价：
¥3800.00
美元价：
2280.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | 2-Hydroxy-4-methoxy-3-(3-methylbut-2-en-1-yl)-6-phenethylbenzoicacid |
| ProductType | Chemical |
| Properties | |
| Formula | C21H24O4 |
| MW | 340.4 |
| CAS | 80489-90-3 |
| Source/HostChemicals | IsolatedfromAmorphafruticosa. |
| PurityChemicals | ≥97%(HPLC) |
| Appearance | Solid. |
| Solubility | SolubleinDMSO,ethanolormethanol.Insolubleinwater. |
| Identity | Determinedby1H-NMRandMS. |
| InChiKey | CTNFTPUIYFUXBE-UHFFFAOYSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Keepcoolanddry. Protectfromlight. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Antidiabeticagent.
- PotentandselectivepartialagoNISTofperoxisomeproliferator-activatedreceptorγ(PPARγ),anuclearreceptorregulatinglipidandglucosemetabolism.HasnanomolarbindingaffinitytoPPARγandmicromolarbindingtotheisotypesPPARαandPPARβ/δ.
- Glucose-loweringagent.Improvesinsulinsensitivity,glucosetoleranceandbloodlipidvariableswithoutincreaseoffatstorageorhepatoxicity.
- ShowspotentPPARγ-dependentanti-inflammatoryactivity.
- PotentNF-κBactivationinhibitorbythesuppressionofIκBαdegradation,p65nucleartranslocationandDNA-bindingactivity.
- Antimicrobialagent.
ProductReferences
- AmorfrutinAandB,bibenzylantimicrobialagentsfromAmorphafruticosa:L.A.Mitscher,etal.;Phytochemistry20,781(1981)
- Amorfrutinsarepotentantidiabeticdietarynaturalproducts:C.Weidner,etal.;PNAS109,7257(2012)
- Structuralcharacterizationofamorfrutinsboundtotheperoxisomeproliferator-activatedreceptorgamma:J.C.DeGroot,etal.;J.Med.Chem.56,1535(2013)
- AmorfrutinAinhibitsTNF-α-inducedNF-κBactivationandNF-κB-regulatedtargetgeneproducts:H.Shi,etal.;Int.Immunopharmacol.21,56(2014)
- Naturalproductagonistsofperoxisomeproliferator-activatedreceptorgamma(PPARγ):areview:L.Wang,etal.;Biochem.Pharmacol.92,73(2014)
- AmorfrutinsAreNaturalPPARγAgonistswithPotentAnti-inflammatoryProperties:L.Fuhr,etal.;J.Nat.Prod.78,1160(2015)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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