脂肪原/阿马他汀。盐酸盐/AG-CP3-7003-M005/5 mg
商品编号：
AG-CP3-7003-M005
品牌：
Adipogen Inc
市场价：
¥3000.00
美元价：
1800.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | [(2S,3R)-3-Amino-2-hydroxy-5-methyl-hexanoyl]-Val-Val-Asp-OH.HCl |
| ProductType | Chemical |
| Properties | |
| Formula | C21H38N4O8.HCl |
| MW | 474.6.36.5 |
| CAS | 100938-10-1 |
| Source/HostChemicals | Synthetic. |
| PurityChemicals | ≥98%(HPLC) |
| Appearance | Whitetooff-whitepowder. |
| Solubility | SolubleinDMF,ethanol,DMSOoraqueoussolvents(PBS). |
| InChiKey | GBDUPCKQTDKNLS-PORDUOSCSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Keepcoolanddry. Protectfrommoisture. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. |
| Documents | |
| Protocols |  DownloadPDF |
| MSDS | DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Slow,tightbindingandcompetitiveaminopeptidase(AP)inhibitor.
- Inhibitscytosolicleucineaminopeptidase,microsomalaminopeptidaseMandbacterialleucineaminopeptidase, humanserumaminopeptidaseA(AP-A),aminopeptidaseN(AP-N),tyrosineaminopeptidase,butnotaminopeptidaseB(AP-B).
- Amastatiniswithouteffectontrypsin,papain,chymotrypsin,elastase,pepsinorThermolysin.
- InhibitscompletelytheSuc-Ala-Ala-Pro-Leu-pNAamidolyticenzyme.
- SlightlyinhibitstheformationofangiotensinIII(AngIII)fromAngiotensinIIthroughAP-A,butsignificantlyincreasesthepotencyofangiotensinIIIand[des-Asp1]-angiotensinI.
- Moderateinhibitorofmitochondrialintermediatepeptidase(MIP).
- Weakinhibitorofsimianimmunodeficiencyvirusprotease(SIV-PR).
ProductReferences
- Amastatin,aninhibitorofaminopeptidaseA,producedbyactinomycetes:T.Aoyagi,etal.;J.Antibiot.31,636(1978)
- Inhibitionofaminopeptidasesbyamastatinandbestatinderivatives.Effectofinhibitorstructureonslow-bindingprocesses:D.H.Rich,etal.;J.Med.Chem.27,417(1984)
- Theslow,tightbindingofbestatinandamastatintoaminopeptidases:S.H.Wilkes&J.M.Prescott;J.Biol.Chem.260,13154(1985)
- Inhibitionofaminopeptidasesbypeptidescontainingketomethyleneandhydroxyethyleneamidebondreplacements:S.L.Harbeson&D.H.Rich;J.Med.Chem.32,1378(1989)
- Roleofaminopeptidaseactivityintheregulationofthepressoractivityofcirculatingangiotensins:S.Ahmad&P.E.Ward;J.Pharmacol.Exp.Ther.252,643(1990)
- Purificationandbiochemicalcharacterizationofrecombinantsimianimmunodeficiencyvirusproteaseandcomparisontohumanimmunodeficiencyvirustype1protease:S.K.Grant,etal.;Biochemistry30,8424(1991)
- Ratlivermitochondrialintermediatepeptidase(MIP):purificationandinitialcharacterization:F.Kalousek,etal.;EMBOJ.11,2803(1992)
- VasopressinandamastatininduceV(1)-receptor-mediatedsuppressionofexcitatorytransmissionintheratparabrachialnucleus:X.Chen&Q.J.Pittman;J.Neurophysiol.82,1689(1999)
- Inhibitorsonanelastase-likeenzymeactivitycatalyzingSuc-Ala-Ala-Pro-Leu-pNAamidolysisinhumanseminalplasma:Y.Matsuda,etal.;Arch.Androl.44,1(2000)
- Themostpotentorganophosphorusinhibitorsofleucineaminopeptidase.Structure-baseddesign,chemistry,andactivity:J.Grembecka,etal.;J.Med.Chem.46,2641(2003)
- Glutamine-181iscrucialintheenzymaticactivityandsubstratespecificityofhumanendoplasmic-reticulumaminopeptidase-1:Y.Goto,etal.;Biochem.J.416,109(2008)
- AngiotensinIIImodulatesthenociceptivecontrolmediatedbytheperiaqueductalgraymatter:A.Pelegrini-da-Silva,etal.;Neurosci.164,1263(2009)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
联络我们
