Adipogen/Actinonin/AG-CN2-0161-M025/25 mg
商品编号：
AG-CN2-0161-M025
品牌：
Adipogen Inc
市场价：
¥7900.00
美元价：
4740.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Details | |
|---|---|
| Synonyms | (-)-Actinonin; CONA 57; Ro 06-1467 |
| Product Type | Chemical |
| Properties | |
| Formula | C19H35N3O5 |
| MW | 385.5 |
| CAS | 13434-13-4 |
| RTECS | RG9900700 |
| Source/Host Chemicals | Synthetic. |
| Purity Chemicals | >97.0% (HPLC) |
| Appearance | White solid. |
| Solubility | Soluble in DMSO or ethanol. |
| Declaration | Synthesized by the Organic Chemistry Group of The Kitasato Institute. |
| InChi Key | XJLATMLVMSFZBN-UHFFFAOYSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
- Antibiotic [1].
- Aminopeptidase M, N and leucine and alanine aminopeptidase inhibitor [2].
- Potent peptide deformylase (PDF) inhibitor [5].
- Inhibits MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-12 and MMP-13, but not MMP-14 [3].
- Anticancer compound. Antiproliferative. Shows antitumor activity in vitro and in vivo [4]
- Apoptosis inducer [6].
- Meprin A inhibitor [7, 8].
Product References
- Actinonin: an antibiotic substance produced by an actinomycete: J.J. Gordon, et al.; Nature 195, 701 (1962)
- Production of actinonin, an inhibitor of aminopeptidase M, by actinomycetes: H. Umezawa, et al.; J. Antibiot. 38, 1629 (1985)
- Analgesic effect of actinonin, a new potent inhibitor of multiple enkephalin degrading enzymes: M. Hachisu, et al.; Life Sci. 41, 235 (1987)
- Antitumor activity of actinonin in vitro and in vivo: Y. Xu, et al.; Clin. Cancer Res. 4, 171 (1998)
- Actinonin, a naturally occurring antibacterial agent, is a potent deformylase inhibitor: D.Z. Chen, et al.; Biochemistry 39, 1256 (2000)
- Actinonin induces apoptosis in U937 leukemia cells: M. Grujic, et al.; Cancer Lett. 223, 211 (2004)
- Actinonin, a meprin inhibitor, protects ischemic acute kidney injury in male but not in female rats: J. Takayama, et al.; Eur. J. Pharmacol. 581, 157 (2007)
- Actinonin, a meprin A inhibitor, protects the renal microcirculation during sepsis: Z. Whang, et al.; Shock 35, 141 (2011)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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