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当前位置: 首页 > 产品中心 > Other_reagents > Adipogen/Ac-Pro-Ala-Leu-AMC [Ac-PAL-AMC]/SBB-PS0007-M002/2 mg
商品详细Adipogen/Ac-Pro-Ala-Leu-AMC [Ac-PAL-AMC]/SBB-PS0007-M002/2 mg
Adipogen/Ac-Pro-Ala-Leu-AMC [Ac-PAL-AMC]/SBB-PS0007-M002/2 mg
Adipogen/Ac-Pro-Ala-Leu-AMC [Ac-PAL-AMC]/SBB-PS0007-M002/2 mg
商品编号: SBB-PS0007-M002
品牌: Adipogen Inc
市场价: ¥2420.00
美元价: 1452.00
产地: 美国(厂家直采)
公司:
产品分类: 其他试剂
公司分类: Other_reagents
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
MoreInformation
ProductDetails
SynonymsProteasomeSubstrate
ProductTypeChemical
Properties
FormulaC26H34N4O6
MW498.6
SequenceAcetyl-Pro-Ala-Leu-7-amido-4-methylcoumarin
CAS1431362-79-6
PurityChemicals≥99%(HPLC)
AppearanceLyophilizedpowder.
SolubilitySolubleinDMSO.
DeclarationManufacturedbySouthBayBio.
OtherProductDataUse:AfterpreparingastocksolutioninDMSO(≥10mM)storeproductat-20°Cto-80°C.Itisrecommendedtomakemultiplealiquotsafterthefirstthawtoensurebestperformance.Caspase-likeactivitycanbemeasuredusingatypicalworkingconcentrationrangefrom10-50µM.ClickhereforaTypicalLot-specificProductDatasheetfromtheOriginalManufacturer
Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet.
InChiKeyBWJPVHDZSJFFDM-NDXORKPFSA-N
ShippingandHandling
ShippingBLUEICE
ShortTermStorage+4°C
LongTermStorage-20°C
HandlingAdviceAvoidfreeze/thawcycles.
Protectfromlight.
Use/StABIlityStableforatleast1yearafterreceiptwhenstoredat-20°C.
Documents
MSDSNo
ProductSpecificationSheet
DatasheetDownloadPDF
Ac-PAL-AMCisafluorogenicpeptidesubstrateformeasuringcaspase-likeactivityoftheimmunoproteasome.Hydrolysisofthissubstratebytheβ1i-subunitoftheimmunoproteasomeismonitoredbyobservingfluorescenceatanExcitationwavelengthof345nmandEmissionat445nm.Thissubstrateisspecifictotheimmunoproteasomeandisnothydrolyzedefficientlybytheconstitutiveproteasome.
ProductReferences
  1. PSMB9codon60polymorphismshavenoimpactontheactivityoftheimmunoproteasomecatalyticsubunitB1iexpressedinmultipletypesofsolidcancer:J.E.Park,etal.;PloSone8,e73732(2013)
  2. Inhibitorsoftheimmunoproteasome:currentstatusandfuturedirections:Z.Miller,etal.;Curr.Pharm.Des.19,4140(2013)
  3. Developmentandcharacterizationofselectiveimmunoproteasomeinhibitors:C.Dubiella;Diss.UniversitaetMuenchen(2015)
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。