Adipogen/7-Dehydrocholesterol/CDX-D0331-G025/25 g
商品编号：
CDX-D0331-G025
品牌：
Adipogen Inc
市场价：
¥3060.00
美元价：
1836.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Details | |
|---|---|
| Synonyms | 7-DHC; NSC 18159; Provitamin D3; Δ7-Cholesterol; (−)-7-Dehydrocholesterol; 3β-Hydroxy-5,7-cholestadiene; 5,7-Cholestadien-3β-ol |
| Product Type | Chemical |
| Properties | |
| Formula | C27H44O |
| MW | 384.64 |
| CAS | 434-16-2 |
| Source/Host Chemicals | Synthetic |
| Purity Chemicals | ≥95% (HPLC) |
| Appearance | White powder. |
| Solubility | Soluble in ethanol, chloroform or ethyl acetate. Slightly soluble in DMSO. Insoluble in water. |
| Identity | Determined by NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| InChi Key | UCTLRSWJYQTBFZ-DDPQNLDTSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
Keep cool and dry. Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS | No |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Precursor of cholesterol and vitamin D3. It is reduced to cholesterol by the enzyme 3β-hydroxysterol-Δ7-reductase (DHCR7) in the last step of cholesterol biosynthesis. Mutations in the gene encoding DHCR7 lead to increased levels of 7-DHC and the neurodevelopmental syndrome Smith-Lemli-Opitz syndrome (SLOS). 7-DHC is used as a biomarker for SLOS screenings. Inhibits human fibroblast sphingomyelinase. Shown to have cytotoxic effects on melanoma cells. In skin, photolysis of 7-DHC by ultraviolet light produces vitamin D3. UV/Vis: λmax 271, 282, 293nm.
Product References
(1) T. Okano, et al.; J. Nutr. Sci. Vitaminol. 24, 47 (1978) | (2) J.c. Maziere, et al.; BBRC 100, 1299 (1981) | (3) Q. Xiong, et al.; Chem. Phys. Lipids 115, 1 (2002) | (4) A. Valencia, et al.; Free. Radic. Biol. Med. 41, 1704 (2006) | (5) M. Gelzo, et al.; Free. Radic. Biol. Med. 70, 129 (2014) | (6) W. Liu, et al.; J. Lipid. Res. 55, 329 (2014)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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