Adipogen/7-Azido-4-methylcoumarin/AG-CR1-3525-M005/5 mg
商品编号：
AG-CR1-3525-M005
品牌：
Adipogen Inc
市场价：
¥1400.00
美元价：
840.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | AzMC |
| ProductType | Chemical |
| Properties | |
| Formula | C10H7N3O2 |
| MW | 201.2 |
| CAS | 95633-27-5 |
| PurityChemicals | ≥98%(NMR) |
| Appearance | Whitetoyellowsolid. |
| Solubility | SolubleinDMSO. |
| Identity | Determinedby1H-NMRandMS. |
| InChiKey | HEKDKVLIMUWRRZ-UHFFFAOYSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Protectfromlight. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. Storesolutionsat-20°Cinthedark. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- HighlysensitiveandselectivefluorogenicH2Sprobe[1-3].ThearomaticazidemoietyofAzMCisselectivelyreducedinthepresenceofH2S,producingthefluorescent7-amino-4-methylcoumarin(AMC)withaconcomitantincreaseinfluorescencewith&lamBDa;ex=365nmandλem=450nm.
- Photoaffinitylabelingprobeforthesubstratebindingsiteofhumansulfotransferase1A1(SULT1A1).
- ProbetomonitortheenzymaticproductionofH2SinvitroandtovisualizeH2Sinlivingcells[2,3].
- Toolformonitoringtheactivityofpyridoxal-5"-phosphate(PLP)-dependentenzymes(e.g.cystathionineβ-synthase(CBS),cystathionineγ-lyase(CGL)andtryptophansynthase(TS))[2].
- Tooltoidentifynovelcystathionineβ-synthase(CBS)inhibitorsandactivators[2].
- Suitableforhigh-throughputscreening[2].
- Caution:UseofthisproductwithDTT,TCEPand/orbiologicalthiolsatconcentrationsof>25mMshouldbeavoidedformaximumefficiency[2].
ProductReferences
- Photoaffinitylabelingprobeforthesubstratebindingsiteofhumanphenolsulfotransferase(SULT1A1):7-azido-4-methylcoumarin:G.Chen,etal.;ProteinSci.8,2151(1999)
- Identificationofcystathionineβ-synthaseinhibitorsusingahydrogensulfideselectiveprobe:M.K.Thorson,etal.;Angew.Chem.Int.Ed.Engl.52,4641(2013)
- Fluorescentprobeforhighlyselectiveandsensitivedetectionofhydrogensulfideinlivingcellsandcardiactissues:B.Chen,etal.;Analyst. 138,946(2013)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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