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Adipogen/5-Dodecanoylaminofluorescein Di-β-D-glucopyranoside/AG-CY1-0001-M001/1 mg
Adipogen/5-Dodecanoylaminofluorescein Di-β-D-glucopyranoside/AG-CY1-0001-M001/1 mg
商品编号：
AG-CY1-0001-M001
品牌：
Adipogen Inc
市场价：
¥3200.00
美元价：
1920.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Details | |
|---|---|
| Synonyms | C12-FDGlu |
| Product Type | Chemical |
| Properties | |
| Formula | C44H55NO16 |
| MW | 853.9 |
| CAS | 149541-10-6 |
| Purity Chemicals | ≥98% (NMR) |
| Appearance | Light yellow powder. |
| Solubility | Soluble in DMSO or methanol. Slightly soluble in water. |
| Identity | Determined by 1H-NMR. |
| InChi Key | SLIWIQKBDGZFQR-BEAWHITJSA-N |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
Keep cool and dry. Protect from light. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
- Non-fluorescent reporter protein substrate. This fluorogenic β-glucosidase substrate releases the highly fluorescent dye 5-dodecanoylaminofluorescein (Spectral data: λex=490nm, λem=520nm) in direct correlation with enzyme activity. Can be used for analysis of cell viability.
- This fluorescent substrate is for measuring the presence and activity of a glycosidic enzyme inside a cell. The substrates can penetrate the cell membrane under physiological conditions and forms a non-toxic green fluorescent product that is well retained in viable cells and which allows sorting and cloning of the cells and monitoring of cell development in vitro and in vivo.
- The colorless and lipophilic substrate enters the cells by embedding in the outer layer of the cell membrane as a glycolipid and then transferring to the inner membrane by a 'flip-flop' mechanism. Once inside the cell, the substrate is cleaved by β-glucosidase, generating the green fluorescent enzymatic hydrolysis product 5-dodecanoylaminofluorescein, which is retained in the cell membrane because of its lipophilic hydrocarbon chain, and allowing histochemical, spectrophotometric and fluorometric measurements.
Product References
- Lipophilic fluorescent glycosidase substrates: R.P. Haugland, et al.; US5208148A (1993)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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