脂肪原/5（6）-羧基DCFDA/CDX-C0042-G001/1 g
商品编号：
CDX-C0042-G001
品牌：
Adipogen Inc
市场价：
¥12940.00
美元价：
7764.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Details | |
|---|---|
| Synonyms | 5(6)-Carboxy-2′,7′-dichlorofluorescein diacetate |
| Product Type | Chemical |
| Properties | |
| Formula | C25H14Cl2O9 |
| MW | 529.28 |
| CAS | 127770-45-0 |
| Source/Host Chemicals | Synthetic. |
| Purity Chemicals | ≥85% (HPCE) |
| Appearance | White to off-white powder. |
| Solubility | Soluble in DMSO, DMF or methanol. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | +4°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Documents | |
| MSDS | No |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Non-activated, amine-reactive fluorescent probe. Mixture of 5/6-isomers of CDCFDA that can be used in biomolecules conjugation. 5(6)-CDCFDA is an amine–reactive fluorescein diacetate (FDA) derivative used to prepare a variety of FDA conjugates. 5(6)-CDCFDA is a non-fluorescent molecule that diffuse into cells and is hydrolyzed by intracellular non-specific esterases, yielding a fluorescent probe. The probe accumulates exclusively in viable cells with intact cell membranes. 5(6)-CDCFDA does not stain dead cells. 5(6)-CDCFDA labeling can be used for monitoring cells by flow cytometry or fluorescence microscopy. The probe is also frequently used to monitor reactive oxygen species (ROS) generation in live cells and intracellular pH levels. Spectral data: λex=504nm, λem=529nm.
Product References
(1) J.P. Kehrer & T. Paraidathathu; Free Rad. Res. Commun. 16, 217 (1992) | (2) Q.P. Lloyd, et al.; J. Biol. Chem. 270, 22445 (1995) | (3) A.L. Inselman, et al.; Curr. Microbiol. 38, 295 (1999) | (4) M.J. Zamek-Gliszczynski, et al.; J. Pharmacol. Exp. Therap. 304, 801 (2003) | (5) L. Li, et al.; Free Radic. Res. 42, 354 (2008) | (6) M. Medhora, et al.; Am. J. Physiol. Lung Cell Mol. Physiol. 294, L902 (2008) | (7) S. Siissalo, et al.; Eur. J. Pharm. Biopharm. 71, 332 (2009) | (8) A.I. Pogue, et al.; Int. J. Mol. Sci. 13, 9615 (2012) | (9) J. Roh, et al.; Redox Biol. 11, 254 (2016) | J.L. Roh, et al.; Cancer Lett. 381, 96 (2016)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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