Adipogen/10,11-Dehydrocurvularin/AG-CN2-0165-M001/1 mg
商品编号：
AG-CN2-0165-M001
品牌：
Adipogen Inc
市场价：
¥2000.00
美元价：
1200.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Details | |
|---|---|
| Synonyms | α,β-Dehydrocurvularin |
| Product Type | Chemical |
| Properties | |
| Formula | C16H18O5 |
| MW | 290.3 |
| CAS | 1095588-70-7 |
| Source/Host Chemicals | Isolated from Aspergillus sp. |
| Purity Chemicals | ≥95% (HPLC) |
| Appearance | Off-white solid. |
| Solubility | Soluble in ethanol, methanol or DMSO. |
| Declaration | Manufactured by BioLinks K.K. with courtesy strain from The Kitasato Institute. |
| InChi Key | AVIRMQMUBGNCKS-OAQKJQOQSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Keep cool and dry. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
- Antibiotic [1, 2, 6].
- Antifungal [6].
- Nematicidal [4].
- Phytotoxic [3].
- TGF-β signaling inhibitor [9]
- Anticancer compound [5, 6, 8, 10].
- Strong activator of the heat shock response [8].
- Inhibitor of the appressorium formation of M. grisea [7]
Product References
- Curvularin. Part V. The compound C16H18O5, αβ-dehydrocurvularin: H.D. Munro, et al.; J. Chem. Soc. C 1967, 947 (1967)
- Isolation of alpha,beta-dehydrocurvularin from Aspergillus aureofulgens: O. Caputo & F. Viola; Planta Med. 31, 31 (1977)
- Brefeldin A and alpha,beta-dehydrocurvularin, two phytotoxins from Alternaria zinniae, a biocontrol agent of Xanthium occidentale: M. Vurro, et al.; Plant Sci. 138, 67 (1998)
- Betagamma-dehydrocurvularin and related compounds as nematicides of Pratylenchus penetrans from the fungus Aspergillus sp.: M. Kusano, et al.; Biosci. Biotechnol. Biochem. 67, 1413 (2003)
- Cytotoxic and other metabolites of Aspergillus inhabiting the rhizosphere of Sonoran desert plants: J. He, et al.; J. Nat. Prod. 67, 1985 (2004)
- Isolation and difference in anti-Staphylococcus aureus bioactivity of curvularin derivates from fungus Eupenicillium sp.: L.W. Xie, et al.; Appl. Biochem. Biotechnol. 159, 284 (2009)
- Alternariol monomethyl ether and α, β-Dehydrocurvularin from endophytic Fungi Alternaria spp. inhibit appressorium formation of Magnaporthe grisea: Y.T. Jeon, et al.; J. Kor. Soc. Appl. Biol. Chem. 53, 39 (2010)
- Characterization of the biosynthetic genes for 10,11-dehydrocurvularin, a heat shock response-modulating anticancer fungal polyketide from Aspergillus terreus: Y. Xu, et al.; Appl. Environ. Microbiol. 79, 2038 (2013)
- Inhibition of TGF-β signaling by the fungal lactones (S)-curvularin, dehydrocurvularin, oxacyclododecindione and galiellalactone: K. Rudolph, et al.; Cytokine 61, 285 (2013)
- Metabolite profiling and biological activities of bioactive compounds produced by Chrysosporium lobatum strain BK-3 isolated from Kaziranga National Park, Assam, India: C.G. Kumar, et al.; Springerplus 2, 122 (2013)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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