Adipogen/(±)-Lisofylline/CDX-H0117-M050/50 mg
商品编号：
CDX-H0117-M050
品牌：
Adipogen Inc
市场价：
¥3520.00
美元价：
2112.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | 1-(5"-Hydroxyhexyl)-3,7-dimethylxanthine;LSF;BL194;CT-1501R;5-Hydroxypentoxifylline |
| ProductType | Chemical |
| Properties | |
| Formula | C13H20N4O3 |
| MW | 280.3 |
| CAS | 6493-06-7 |
| Source/HostChemicals | Synthetic. |
| PurityChemicals | ≥99%(HPLC) |
| Appearance | Whitepowder. |
| Solubility | Solubleinchloroform. |
| Identity | DeterminedbyNMR. |
| Declaration | ManufacturedbyChemodex. |
| OtherProductData | ClickhereforOriginalManufacturerProductDatasheet Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet. |
| InChiKey | NSMXQKNUPPXBRG-UHFFFAOYSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Keepcoolanddry. Protectfromlightandmoisture. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
Syntheticmethylxanthinemetaboliteofpentoxifylline.Potentanti-inflammatoryagentinwhichonlythe(−)opticalisomerisBIOLOGicallyactive.Inhibitsthegenerationofphosphatidicacidfromcytokine-activatedlysophosphatidicacyltransferase(LPAAT),whichhasbeenshowntoprotectmicefromendotoxicshock.Decreaseslipidperoxidationinvitroandinvivo.SuppressestheproductionoftheproinflammatorycytokineIFN-γ,inhibitsIL-12-mediatedSTAT-4activation,enhancesglucose-stimulatedβ-cellinsulinsecretion,reducingtheonsetofdiabetesinanon-obesediabeticmousemodel,andblocksautoimmunedeteriorationofpancreaticβcellsinnon-obesediabeticmice.Compoundcanbeusedasanalyticalreferencematerial.
ProductReferences
(1)G.C.Rice,etal.;PNAS91,3857(1994)|(2)E.Clarke,etal.;CancerRes.56,105(1996)|(3)N.Hasegawa,etal.;Am.J.Respir.Crit.CareMed.155,928(1997)|(4)S.Itani,etal.;Metabolism50,553(2001)|(5)S.Itani,etal.;Diabetes51,2005(2002)|(6)M.Chen,etal.;Endocrinol.143,2341(2002)|(7)Z.Yang,etal.;Ann.N.Y.Acad.Sci.1005,409(2003)|(8)J.S.Striffler,etal;.Metab.Clin.Exp.53,290(2004)|(9)Z.Yang,etal.;Biochem.Pharmacol.69,1(2005)|(10)E.Wyska;Pharmacology85,264(2010)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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