Adipogen/(S)-(+)-Naproxene/CDX-N0061-G001/1 g
商品编号：
CDX-N0061-G001
品牌：
Adipogen Inc
市场价：
¥580.00
美元价：
348.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | Naprosyn;Equiproxen;Laraflex;(S)-(+)-6-Methoxy-α-methyl-2-naphthaleneaceticacid |
| ProductType | Chemical |
| Properties | |
| Formula | C14H14O3 |
| MW | 230.26 |
| CAS | 22204-53-1 |
| RTECS | UF5275000 |
| Source/HostChemicals | Synthetic |
| PurityChemicals | ≥98%(HPLC) |
| Appearance | Whitepowder. |
| Solubility | Solubleinwater(>3mg/mlat25°C),methanol,DMSO,DMF(100mg/ml),chloroform,dichloromethane,ether,ethylacetateortetrahydrofuran. |
| Identity | DeterminedbyNMR. |
| Declaration | ManufacturedbyChemodex. |
| OtherProductData | ClickhereforOriginalManufacturerProductDatasheet Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet. |
| InChiKey | CMWTZPSULFXXJA-UHFFFAOYSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | +4°C |
| HandlingAdvice | Keepcoolanddry. Protectfromlightandmoisture. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat+4°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
Non-selectiveCOXinhibitor.TheIC50valuesforhumanrecombinantCOX-1and-2are0.6-4.8µMand2.0-28.4µM,respectively.Naproxenisapotent,non-steroidal,non-selectiveanti-inflammatorycompoundthatactsasaCox(cyclooxygenase)inhibitor,andinhibitsbothCox-1andCox-2.ResearchindicatesthattheS-naproxenisamoreactiveformthantheR-naproxen.TheS-naproxenenantiomerwasobservedtoinhibitplateletaggregation,andbothenantiomersdecreaseproductionofthromboxaneB2.NaproxenhasbeendemonstratedtoblockAβfibrilgrowthandformacomplexwithcopper(II).
ProductReferences
(1)I.T.Harrisonetal.,J.Med.Chem.13,203(1970)|(2)R.N.Brogden,etal.;Drugs18,241-277(1979)|(3)W.F.Kean,etal.;J.Pharm.Sci.78,324(1989)|(4)K.C.Duggan,etal.;J.Biol.Chem.285,34950(2010)|(5)T.Takeda,etal.;J.Phys.Chem.B.114,15394(2010)|(6)F.Dimiza,etal.;J.Inorg.Biochem.105,476(2011)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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