Adipogen/(R,R)-Hymeglusin/AG-CN2-0103-MM25/2.5 mg
商品编号：
AG-CN2-0103-MM25
品牌：
Adipogen Inc
市场价：
¥10000.00
美元价：
6000.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | 1233A;F-244;L-659-699 |
| ProductType | Chemical |
| Properties | |
| Formula | C18H28O5 |
| MW | 324.4 |
| CAS | 29066-42-0 |
| Source/HostChemicals | IsolatedfromfungalstrainScopulariopsissp.F-244. |
| PurityChemicals | ≥95%(HPLC) |
| Appearance | Whitetooff-whitesolid. |
| Solubility | Solubleinmethanol,ethanol,DMSO,chloroformorethylacetate.Insolubleinwaterorhexane. |
| Declaration | ManufacturedbyBiOlinksK.K.withcourtesystrainfromTheKitasatoInstitute. |
| InChiKey | ODCZJZWSXPVLAW-KXCGKLMDSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Afterreconstitution,preparealiquotsandstoreat-20°C. |
| Use/StABIlity | Stableforatleast3yearsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- β-Lactoneantibiotic[1].
- Antibacterialandantifungal[1,4].
- SpecificandirreversIBLeinhibitorof3-hydroxy-3-methylglutarylcoenzymeA(HMG-CoA)synthaseinvitroandinvivobycovalentlymodifyingtheactiveCys129residueoftheenzyme[2-4,6-8].
- Mevalonatebiosynthesisinhibitor[5].
ProductReferences
- Antibiotic1233A:afungalbeta-lactone:D.C.Aldridge,etal.;J.Chem.Soc.23,3888(1971)
- Potentinhibitoryeffectofantibiotic1233Aoncholesterolbiosynthesiswhichspecificallyblocks3-hydroxy-3-methylglutarylcoenzymeAsynthase:S.Omura,etal.;J.Antibiot.(Tokyo)40,1356(1987)
- F-244specificallyinhibits3-hydroxy-3-methylglutarylcoenzymeAsynthase:H.Tomoda,etal.;Biochim.Biophys.Acta922,351(1987)
- F-244(1233A),aspecificinhibitorof3-hydroxy-3-methylglutarylcoenzymeAsynthase:taxonomyofproducingstrain,fermentation,isolationandBIOLOGicalproperties:H.Tomoda,etal.;J.Antibiot.(Tokyo)41,247(1988)
- Methodofsearchformicrobialinhibitorsofmevalonatebiosynthesisusinganimalcells:H.Kumagai,etal.;J.Antibiot.(Tokyo)43,397(1990)
- Specificbindingofbeta-lactone1233Ato3-hydroxy-3-methylglutaryl-coenzymeAsynthase:H.Tomoda,etal.;J.Antibiot.(Tokyo)46,872(1993)
- Inhibitionofhepaticcholesterolbiosynthesisbya3-hydroxy-3-methylglutarylcoenzymeAsynthaseinhibitor,1233A,inmice:H.Nagashima,etal.;LifeSci.52,1595(1993)
- Bindingsiteforfungalbeta-lactonehymeglusinoncytosolic3-hydroxy-3-methylglutarylcoenzymeAsynthase:H.Tomoda,etal.;Biochim.Biophys.Acta1636,22(2004)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
联络我们
