Adipogen/(3S,6R)-Lateritin/AG-CN2-0042-M001/1 mg
商品编号：
AG-CN2-0042-M001
品牌：
Adipogen Inc
市场价：
¥3200.00
美元价：
1920.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | (3S,6R)-Bassiatin;AntibioticPI290 |
| ProductType | Chemical |
| Properties | |
| Formula | C15H19NO3 |
| MW | 261.3 |
| CAS | 65454-13-9 |
| Source/HostChemicals | IsolatedfromfungusGibberellasp. |
| PurityChemicals | ≥97%(HPLC) |
| Appearance | Off-whitesolid. |
| Solubility | SolubleinethanolorDMSO. |
| Identity | Determinedby1H-NMR. |
| InChiKey | YOKBTBNVNCFOBF-QWHCGFSZSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Keepcoolanddry. Protectfromlight. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. Storesolutionsat-20°Cinthedark. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- N-methylatedpeptidethatisstructurallyequivalenttoamonomerofbeauvericin(Prod.No.AG-CN2-0043)[3,4].
- Acyl-CoA:cholesterolacyltransferase(ACAT)inhibitor[1,5].
- Plateletaggregationinhibitor[2,5].
- Antimicrobial[5].
- Note:The(3R,6R)-stereoisomerwasshowntohaveanti-cancerandapoptosisinducingactivity[5-7].
ProductReferences
- Lateritin,anewinhibitorofacyl-CoA:cholesterolacyltransferaseproducedbyGibberellalateritiumIFO7188:K.Hasumi,etal.;J.Antibiot.(Tokyo).46,1782(1993)
- Bassiatin,anewplateletaggregationinhibitorproducedbyBeauveriabassianaK-717:T.Kagamizono,etal.;J.Antibiot.(Tokyo).48,1407(1995)
- Beauvericininducescytotoxiceffectsinhumanacutelymphoblasticleukemiacellsthroughcytochromecrelease,caspase3activation:thecausativeroleofcalcium:G.M.Jow,etal.;CancerLett.216,165(2004)
- BeauvericinactivatesCa2+-activatedCl-currentsandinducescelldeathsinXenopusoocytesviainfluxofextracellularCa2+:C.Y.Tang,etal.;Chem.Res.Toxicol.18,825(2005)
- Isolationofhumancancercellgrowthinhibitory,antimicrobiallateritinfromamixedfungalculture:R.K.Pettit,etal.;PlantaMed.76,500(2010)
- (3R,6R)-4-methyl-6-(1-methylethyl)-3-phenylmethyl-perhydro-1,4-oxazine-2,5-dione:anapoptosis-inducerfromthefruitingbodiesofIsariajaponica:H.Oh,etal.;PlantaMed.68,345(2002)
- Anovelantioestrogenagent(3R,6R)-bassiatininhibitscellproliferationandcellcycleprogressionbyrepressingcyclinD1expressionin17β-oestrADIol-treatedMCF-7cells:L.Meng,etal.;CellBiol.Int.35,599(2011)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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