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当前位置: 首页 > 产品中心 > Other_reagents > Adipogen/(-)-Viriditoxin/AG-CN2-0471-C500/500 µg
商品详细Adipogen/(-)-Viriditoxin/AG-CN2-0471-C500/500 µg
Adipogen/(-)-Viriditoxin/AG-CN2-0471-C500/500 µg
Adipogen/(-)-Viriditoxin/AG-CN2-0471-C500/500 µg
商品编号: AG-CN2-0471-C500
品牌: Adipogen Inc
市场价: ¥2400.00
美元价: 1440.00
产地: 美国(厂家直采)
公司:
产品分类: 其他试剂
公司分类: Other_reagents
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
MoreInformation
ProductDetails
Synonyms(M)-Viriditoxin;SC-28762
ProductTypeChemical
Properties
FormulaC34H30O14
MW662.6
CAS1381782-08-6
Source/HostChemicalsIsolatedfromfungusAspergillussp.
PurityChemicals≥98%(HPLC)
AppearanceSolid.
SolubilitySolubleinDMSOorethanol.
IdentityDeterminedby1H-NMR.
InChiKeyGMCZVCXZGZGZPX-HOTGVXAUSA-N
ShippingandHandling
ShippingAMBIENT
ShortTermStorage+4°C
LongTermStorage-20°C
HandlingAdviceProtectfromlight.
Use/StABIlityStableforatleast2yearsafterreceiptwhenstoredat-20°C.
Documents
MSDSDownloadPDF
ProductSpecificationSheet
DatasheetDownloadPDF
  • Antibiotic.ExhibitsbroadactivityagainstGram-positivebacteria.
  • BacterialcelldivisionproteinFtsZinhibitor(IC50=8.2µg/ml).InhibitstheGTPaseactivityofFtsZinvitro(IC50=7.0µg/ml).
  • InducesapoptosisandautophagyandinhibitscellgrowthatG2/Minhumanprostatecancercells.
  • ActivatesATPhydrolysisandinducescalciumsensitizedswellingofratlivermitochondria.
ProductReferences
  1. ViriditoxinproductionbyAspergillusviridi-nutansandrelatedspecies:E.B.Lillehoj&M.S.Milburn;Appl.Microbiol.26,202(1973)
  2. MetabolicproductsfromSpicariadivaricataNRRL5771:J.JiuS.Mizuba;J.Antibiot.(Tokyo)27,760(1974)
  3. Viriditoxininducesswellingandatpasebyactivationofcalciumtransportinlivermitochondria:D.T.Wong&R.L.Hamill;BBRC71,332(1976)
  4. DiscoveryofasmallmoleculethatinhibitscelldivisionbyblockingFtsZ,anoveltherapeutictargetofantibiotics:J.Wang,etal.;J.Biol.Chem.278,44424(2003)
  5. Second-GenerationSynthesisof(-)-Viriditoxin:C.I.Grove&J.T.Shaw;Synthesis2012,362(2012)
  6. Viriditoxinregulatesapoptosisandautophagyviamitoticcatastropheandmicrotubuleformationinhumanprostatecancercells:S.Kundu,etal.;Int.J.Oncol.45,2331(2014)
  7. Atwistofnature-thesignificanceofatropisomersinBIOLOGicalsystems:J.E.Smyth,etal.;Nat.Prod.Rep.32,1562(2015)
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。