Adipogen/(+)-Catechin . hydrate/AG-CN2-0407-G001/1 g
商品编号：
AG-CN2-0407-G001
品牌：
Adipogen Inc
市场价：
¥800.00
美元价：
480.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | Cianidanol;Cyanidol;Catechol;Catechuicacid;NSC2819;(+)-3,3",4",5,7-Flavanpentol |
| ProductType | Chemical |
| Properties | |
| Formula | C15H14O6.H2O |
| MW | 290.3.18.0 |
| MerckIndex | 14:1902 |
| CAS | 225937-10-0or88191-48-4 |
| Source/HostChemicals | IsolatedfromUncariarhynchophylla. |
| PurityChemicals | ≥95%(NMR) |
| Appearance | Off-whitepowder. |
| Solubility | SolubleinDMSO,ethanolordimethylformamide.Sparinglysolubleinwater. |
| Identity | Determinedby1H-NMR. |
| InChiKey | OFUMQWOJBVNKLR-NQQJLSKUSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Keepcoolanddry. Keepunderinertgas. Protectfromlight. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. Afterreconstitution,preparealiquotsandstoreat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Specifichistidinedecarboxylaseinhibitor[1].
- Anti-inflammatory.COX-1inhibitor[2].
- Antioxidantflavonoid.FreerADIcalscavenger.Inhibitslipidperoxidation[3,6,9].
- Antimetastaticandanticancercompound[4,9,10,14,16,17].
- Antiangiogenic[14].
- Anti-osteoporotic[5].
- Antibacterialandantifungal[7].
- Neuroprotective[8].MonooxidaseBinhibitor[11].
- Apoptosisandcellcyclearrestinducer[9,10,16,17].
- JNKphosphorylationinhibitor[12].
- Antispasmodic[13].
- Insulin-mimetic[15].
ProductReferences
- Histamineandacutehaemorrhagiclesionsinratgastricmucosa:preventionofstressulcerformationby(+)-catechin,aninhibitorofspecifichistidinedecarboxylaseinvitro:H.J.Reimann,etal.;AgentsActions7,69(1977)
- Flavan-3-olsisolatedfromsomemedicinalplantsinhibitingCOX-1andCOX-2catalysedprostaglandinbiosynthesis:Y.Noreen,etal.;PlantaMed.64,520(1998)
- (+)-Catechinasantioxidant:mechanismspreventinghumanplasmaoxidationandactivityinredwines:S.B.Lotito&C.G.Fraga;Biofactors10,125(1999)
- Flavonoidsasanticanceragents:structure-activityrelationshipstudy:M.Lopez-Lazaro;Curr.Med.Chem.AnticancerAgents 2,691(2002)(Review)
- Effectsof(+)-catechinonthefunctionofosteoblasticcells:E.M.Choi&J.K.Hwang;Biol.Pharm.Bull.26, 523(2003)
- Dietarysupplementationof(+)-catechinprotectsagainstUVB-inducedskindamagebymodulatingantioxidantenzymeactivities:S.E.Jeon,etal.;Photodermatol.Photoimmunol.Photomed.19,235(2003)
- Phytotoxicandantimicrobialactivitiesofcatechinderivatives:R.Veluri,etal.;J.Agric.FoodChem.52,1077(2004)
- Catechinpolyphenols:neurodegenerationandneuroprotectioninneurodegenerativediseases:S.Mandel&M.B.Youdim;FreeRadic.Biol.Med.37,304(2004)(Review)
- Agreenteacomponent,catechin,rapidlyinducesapoptosisofmyeloidleukemiccellsviamodulationofreactiveoxygenspeciesproductioninvitroandinhibitstumorgrowthinvivo:L.Gordon;Haematologica90,290(2005)
- (+)-Catechin,aningredientofgreentea,protectsmurinemicrogliafromoxidativestress-inducedDNAdamageandcellcyclearrest:Q.Huang,etal.;J.Pharmacol.Sci.98,16(2005)
- MonoamineoxidaseB(MAO-B)inhibitionbyactiveprinciplesfromUncariarhynchophylla:W.C.Hou;J.Ethnopharmacol.100,216(2005)
- (+)-CatechinpreventsultravioletB-inducedhumankeratinocytedeathviainhibitionofJNKphosphorylation:W.B.Wu,etal.;LifeSci. 79,801(2006)
- Antispasmodic,bronchodilatorandvasodilatoractivitiesof(+)-catechin,anaturallyoccurringflavonoid:M.N.Ghayur,etal.;Arch.Pharm.Res. 30,970(2007)
- (+)-CatechininhibitstumourangiogenesisandregulatestheproductionofnitricoxideandTNF-alphainLPS-stimulatedmacrophages:C.Guruvayoorappan&G.Kuttan;InnateImmun.14,160(2008)
- InsulinmimeticimpactofCatechinisolatedfromCassiafistulaontheglucoseoxidationandmolecularmechanismsofglucoseuptakeonStreptozotocin-induceddiabeticWistarrats:P.Daisy,etal.;Phytomedicine17,28(2010)
- CatechinhydratesuppressesMCF-7proliferationthroughTP53/Caspase-mediatedapoptosis:A.A.Alshatwi;J.Exp.Clin.CancerRes.29,167(2010)
- CatechinhydrateinhibitsproliferationandmediatesapoptosisofSiHahumancervicalcancercells:A.A.Al-Hazzani&A.A.Alshatwi;FoodChem.Toxicol.49,3281(2011)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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