
Adipogen/(+)-Brefeldin A/AG-CN2-0018-M025/25 mg
商品编号:
AG-CN2-0018-M025
品牌:
Adipogen Inc
市场价:
¥2400.00
美元价:
1440.00
产品分类:
其他试剂
公司分类:
Other_reagents
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
ProductDetails | |
---|---|
Synonyms | Ascotoxin;Decumbin;Cyanein;Synergisidin |
ProductType | Chemical |
Properties | |
Formula | C16H24O4 |
MW | 280.4 |
MerckIndex | 14:1369 |
CAS | 20350-15-6 |
Source/HostChemicals | IsolatedfromPenicilliumjanthinellum. |
PurityChemicals | ≥98%(HPLC) |
Appearance | Whitetooff-whitepowder. |
Solubility | Solubleinacetone,DMSO,methanolorethylacetate(1mg/ml). |
Identity | Determinedby1H-NMR. |
InChiKey | KQNZDYYTLMIZCT-KQPMLPITSA-N |
ShippingandHandling | |
Shipping | AMBIENT |
ShortTermStorage | +4°C |
LongTermStorage | -20°C |
Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. Afterreconstitutionprotectfromlightat-20°C. |
Documents | |
MSDS | ![]() |
ProductSpecificationSheet | |
Datasheet | ![]() |
- ProteintransportfromERtoGolgiinhibitor[2,3].
- ADP-ribosylationfactor(Arf)inhibitor[6].
- Cytotoxic[1].
- Antibiotic[8].
- Antiviral[8].
- Apoptosisinducer[5].
- Antitumorcompound[9].
- Intracellularcollagendegradationinhibitor[7].
- Reviews[4,7,8].
ProductReferences
- Decumbin,anewcompoundfromaspeciesofPenicillium:V.L.Singleton,etal.;Nature181,1072(1958)
- NovelblockadebybrefeldinAofintracellulartransportofsecretoryproteinsinculturedrathepatocytes:Y.Misumi,etal.;J.Biol.Chem.261,11398(1986)
- BrefeldinAcausesdisassemblyoftheGolgicomplexandaccumulationofsecretoryproteinsintheendoplasmicreticulum:T.Fujiwara,etal.;J.Biol.Chem.263,18545(1988)
- BrefeldinAandtheendocyticpathway.PossIBLeimplicationsformembranetrafficandsorting:W.Hunziker,etal.;FEBSLett.307,93(1992)(Review)
- BrefeldinAisapotentinducerofapoptosisinhumancancercellsindependentlyofp53:R.G.Shao,etal.;Exp.CellRes.227,190(1996)
- InhibitionbybrefeldinAofaGolgimembraneenzymethatcatalysesexchangeofguaninenucleotideboundtoARF:J.B.Helms&J.E.Rothman;Nature360,352(1992)
- BrefeldinA:decipheringanenigmaticinhibitorofsecretion:A.NEBenfuhr,etal.;PlantPhysiol.130,1102(2002)(Review)
- BIOLOGicaleffectsoftheantibioticbrefeldinA(decumbin,cyanein,ascotoxin,synergisidin):aretrospective:V.Betina;FoliaMicrobiol.(Praha)37,3(1992)(Review)
- ThecytotoxicagentsNSC-95397,brefeldinA,bortezomibandsanguinarineinduceapoptosisinneuroendocrinetumorsinvitro:D.E.Larsson,etal.;AnticancerRes.30,149(2010)
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。
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