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当前位置: 首页 > 产品中心 > Other_reagents > Adipogen/(+)-Brefeldin A/AG-CN2-0018-M025/25 mg
商品详细Adipogen/(+)-Brefeldin A/AG-CN2-0018-M025/25 mg
Adipogen/(+)-Brefeldin A/AG-CN2-0018-M025/25 mg
Adipogen/(+)-Brefeldin A/AG-CN2-0018-M025/25 mg
商品编号: AG-CN2-0018-M025
品牌: Adipogen Inc
市场价: ¥2400.00
美元价: 1440.00
产地: 美国(厂家直采)
公司:
产品分类: 其他试剂
公司分类: Other_reagents
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
MoreInformation
ProductDetails
SynonymsAscotoxin;Decumbin;Cyanein;Synergisidin
ProductTypeChemical
Properties
FormulaC16H24O4
MW280.4
MerckIndex14:1369
CAS20350-15-6
Source/HostChemicalsIsolatedfromPenicilliumjanthinellum.
PurityChemicals≥98%(HPLC)
AppearanceWhitetooff-whitepowder.
SolubilitySolubleinacetone,DMSO,methanolorethylacetate(1mg/ml).
IdentityDeterminedby1H-NMR.
InChiKeyKQNZDYYTLMIZCT-KQPMLPITSA-N
ShippingandHandling
ShippingAMBIENT
ShortTermStorage+4°C
LongTermStorage-20°C
Use/StABIlityStableforatleast1yearafterreceiptwhenstoredat-20°C.
Afterreconstitutionprotectfromlightat-20°C.
Documents
MSDSDownloadPDF
ProductSpecificationSheet
DatasheetDownloadPDF
  • ProteintransportfromERtoGolgiinhibitor[2,3].
  • ADP-ribosylationfactor(Arf)inhibitor[6].
  • Cytotoxic[1].
  • Antibiotic[8].
  • Antiviral[8].
  • Apoptosisinducer[5].
  • Antitumorcompound[9].
  • Intracellularcollagendegradationinhibitor[7].
  • Reviews[4,7,8].
ProductReferences
  1. Decumbin,anewcompoundfromaspeciesofPenicillium:V.L.Singleton,etal.;Nature181,1072(1958)
  2. NovelblockadebybrefeldinAofintracellulartransportofsecretoryproteinsinculturedrathepatocytes:Y.Misumi,etal.;J.Biol.Chem.261,11398(1986)
  3. BrefeldinAcausesdisassemblyoftheGolgicomplexandaccumulationofsecretoryproteinsintheendoplasmicreticulum:T.Fujiwara,etal.;J.Biol.Chem.263,18545(1988)
  4. BrefeldinAandtheendocyticpathway.PossIBLeimplicationsformembranetrafficandsorting:W.Hunziker,etal.;FEBSLett.307,93(1992)(Review)
  5. BrefeldinAisapotentinducerofapoptosisinhumancancercellsindependentlyofp53:R.G.Shao,etal.;Exp.CellRes.227,190(1996)
  6. InhibitionbybrefeldinAofaGolgimembraneenzymethatcatalysesexchangeofguaninenucleotideboundtoARF:J.B.Helms&J.E.Rothman;Nature360,352(1992)
  7. BrefeldinA:decipheringanenigmaticinhibitorofsecretion:A.NEBenfuhr,etal.;PlantPhysiol.130,1102(2002)(Review)
  8. BIOLOGicaleffectsoftheantibioticbrefeldinA(decumbin,cyanein,ascotoxin,synergisidin):aretrospective:V.Betina;FoliaMicrobiol.(Praha)37,3(1992)(Review)
  9. ThecytotoxicagentsNSC-95397,brefeldinA,bortezomibandsanguinarineinduceapoptosisinneuroendocrinetumorsinvitro:D.E.Larsson,etal.;AnticancerRes.30,149(2010)
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。