脂肪原/&alpha-甘露糖神经酰胺/AG-CR1-3594-M001/1毫克
商品编号：
AG-CR1-3594-M001
品牌：
Adipogen Inc
市场价：
¥4900.00
美元价：
2940.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | α-ManCer;α-MannosylCeramide;(2S,3S,4R)-2-Amino-N-hexacosanoyl-1-O-(α-D-mannopyranosyl)-1,3,4-octadecanetriol;α-D-Galactopyranoside |
| ProductType | Chemical |
| Properties | |
| Formula | C50H99NO9 |
| MW | 858.3 |
| CAS | 320610-63-7 |
| PurityChemicals | ≥95%(TLC) |
| Appearance | Whitetooff-whitesolid. |
| Solubility | SolubleinpyridineorwarmDMSO. |
| OtherProductData | NaturalkillerTcells(NKTcells)areimportantregulatorsoftheimmunesystem.Theysharepropertiesofbothinnateaswellasadaptiveimmunity.TheyexpressTcellreceptors(TCR)ontheirsurfaceconsistingofaninvariableα-chainandasomewhatvariableβ-chain.ThemajorityofNKTcellsexpresstheinvariableα-chainVα14-Jα18(Vα14)inmouseoritshomologinhumansVα24-Jα18(Vα24).Vα14NKTcellsrecognizeα-GalCerpresentedbyCD1d.NKTcellsexpressingtheinvariantVα19-Jα26TCRα-chain(Vα19NKTcells)havebeenfoundinperipheralbloodlymphocytesandintheliver.Theyrecognizeα-ManCerpresentedbyMR1(Majorhistocompatibilitycomplex,classI-related)andrespondwithproductionoflargeamountsofimmunoregulatorycytokines. |
| InChiKey | VQFKFAKEUMHBLV-CIKDURTISA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Afterreconstitution,preparealiquotsandstoreat-20°C. Aliquotintoglassvials. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- PotentstimulatorofnaturalkillerT(NKT)cellsexpressingtheinvariantVα19-Jα26Tcellreceptorαchain(Vα19NKTcells).
ProductReferences
- CD1d-restrictedandTCR-mediatedactivationofvalpha14NKTcellsbyglycosylceramides:T.Kawano,etal.;Science278,1626(1997)
- Syntheticalpha-mannosylceramideasapotentstimulantforanNKTcellrepertoirebearingtheinvariantValpha19-Jalpha26TCRalphachain:N.Okamoto,etal.;Chem.Biol.12,677(2005)
- MR1-restrictedValpha19iTcells:asecondpopulationrecognizinglipidantigens?:J.Schumann&G.DeLibero;Eur.J.Immunol.37,1724(2007)
- InductionofpromotiveratherthansuppressiveimmuneresponsesfromanovelNKTcellrepertoireValpha19NKTcellwithalpha-mannosylceramideanaloguesconsistingoftheimmunosuppressantISP-Iasthesphingosineunit:M.Shimamura,etal.;Eur.J.Med.Chem.41,569(2006)
- ModulationofValpha19NKTcellimmuneresponsesbyalpha-mannosylceramidederivativesconsistingofaseriesofmodifiedsphingosines:M.Shimamura,etal.;Eur.J.Immunol.37,1836(2007)
- GlycolipidstimulatorsforNKTcellsbearinginvariantValpha19-Jalpha33TCRalphachains:M.Shimamura;MiniRev.Med.Chem.8,285(2008)
- Non-reducingendalpha-mannosylatedglycolipidsaspotentactivatorsforinvariantValpha19TCR-bearingnaturalkillerTcells:M.Shimamura;Carbohydr.Res.343,2010(2008)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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