Adipogen/UbiCREST Enzyme Set/AG-44T-0139-KI01/1 Set
商品编号：
AG-44T-0139-KI01
品牌：
Adipogen Inc
市场价：
¥13700.00
美元价：
8220.00
产品分类：
其它检测试剂盒
公司分类：
Other_kits
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| ProductType | Set |
| Properties | |
| ApplicationSet | CompoundScreening |
| KitContains | 25µlof10XOtubain1(OTUB1) 25µlof10XGST-AMSH 25µlof10XOTUD3(catalyticdomain) 25µlof10XHis6-TrABId 25µlof10XCezanne(catalyticdomain) 25µlof10XYod1 25µlof10XOtulin(full-length) 25µlof10XUSP2(catalyticdomain) 1.5mlof10XDUBReactionBuffer NOTE:Kitcontainsreagentssufficientfor5UbiCRESTanalysisexperiments. |
| OtherProductData | Use:UbiCREST(UbiquitinChainRestrictionAnalysis)isdesignedtoanalyzetheubiquitinlinkagespresentinfreepolyubiquitinchainsorpolyubiquitinchainsconjugatedtoasubstrateprotein.TheUbiCRESTapproachutilizestheLinkage-specificityoftheovariantumordomain(OTU)classofdeubiquitinases(DUBs)tocharacterizethelinkagespresentinasamplecontainingpolyubiquitin.ThiskitprovidesDUBsthatareusefulforinvitroanalysisofusersuppliedpolyubiquitinatedproteinsamples.Thesamplesmaybegeneratedbyinvitroubiquitinationreactions,orobtainedfromcelllysatesorothercomplexmixturesfollowingimmunoprecipitationorothermeansofpurification. |
| Declaration | ManufacturedbyBostonBiochem |
| ShippingandHandling | |
| Shipping | DRYICE |
| ShortTermStorage | -20°C |
| LongTermStorage | -80°C |
| HandlingAdvice | Aliquottoavoidfreeze/thawcycles. |
| Use/Stability | Stableforatleast1yearafterreceiptwhenstoredat-80°C. |
| Documents | |
| Manual |  DownloadPDF |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
Covalentattachmentofubiquitintotargetproteinsisoneofthemostversatileandintriguingpost-translationalmodificationobservedineukaryoticorganisms.Becausepolyubiquitinchainsmaybegeneratedbyconnectingadjacentubiquitinmoleculesinoneofeightdifferentorientations,alargenumberofvariedarchitecturesmaybegenerated.Polyubiquitinationofproteinsdirectsthemtodifferentcellularfatessuchastranslocationtodifferentareaswithinthecell,assemblyintomulti-subunitcomplexes,ordegradationviatheproteasome,dependingonthetypeoflinkageusedinthepolyubiquitinchain.Recentstudieshavebeguntodefinetherolesofthesedifferentpolyubiquitinsignalsinphysiologyanddisease,anditisobviousthatidentifyingandunderstandingtheusesofthevariouslinkageswillbeimportantinunderstandingandtreatinghumandisease.PolyubiquitinchainsaretypicallyformedviatheE1,E2,E3enzymeconjugationcascadewheretheC-terminalglycineofoneubiquitinislinkedtotheε-aminogroupofalysineonanotherubiquitin;thislinkageisreferredtoasanisopeptidebond.PolyubiquitinchainsofallpossIBLelinkagesincludingK6-,K11-,K27-,K29-,K33-,K48-,K63-,andMet1-linked(or"linear")havebeendetectedinvivo.
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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