脂肪原/TRAIL-R1至-R4流式细胞仪包/AG-44B-0004-KI01/1套
商品编号:
AG-44B-0004-KI01
品牌:
Adipogen Inc
市场价:
¥23000.00
美元价:
13800.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| ProductType | Set |
| Properties | |
| ApplicationSet | Flowcytometry |
| Crossreactivity | Human |
| KitContains | 100μgeachof: anti-TRAIL-R1(cloneHS101,Prod.No.AG-20B-0022); anti-TRAIL-R2(cloneHS201,Prod.No.AG-20B-0023); anti-TRAIL-R3(cloneHS301,Prod.No.AG-20B-0024); anti-TRAIL-R4(cloneHS402,Prod.No.AG-20B-0025). |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Afterreconstitution,preparealiquotsandstoreat-20°C. Avoidfreeze/thawcycles. |
| Use/StABIlity | Stableforatleast6monthsafterreceiptwhenstoredat-20°C. |
| Documents | |
| Manual | No |
| MSDS | DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
TRAIL-R1,-R2,-R3and-R4arereceptorsforthecytotoxicligandTRAIL.WhensignalingthroughTRAIL-R1and-R2,theadaptermoleculeFADDrecruitscaspase-8totheactivatedreceptor.Theresultingdeath-inducingsignalingcomplex(DISC)performscaspase-8proteolyticactivationwhichinitiatesthesubsequentcascadeofcaspases(aspartate-specificcysteineproteases)mediatingapoptosis.TheypromotetheactivationofNF-κB.TRAIL-R3lacksacytoplasmicdeathdomain,andTRAIL-R4containsatruncateddeathdomain,andhencearenotcapableofinducingapoptosis.TheyprotectcellsagainstTRAILmediatedapoptosisbycompetingwithTRAIL-R1andR2forbindingtotheligand.
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。
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