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4000-520-616
当前位置: 首页 > 产品中心 > Functional_antibody > Adipogen/anti-Transthyretin, mAb (10E1)/YIF-LF-MA0174/100 µl
商品详细Adipogen/anti-Transthyretin, mAb (10E1)/YIF-LF-MA0174/100 µl
Adipogen/anti-Transthyretin, mAb (10E1)/YIF-LF-MA0174/100 µl
Adipogen/anti-Transthyretin, mAb (10E1)/YIF-LF-MA0174/100 µl
商品编号: YIF-LF-MA0174
品牌: Adipogen Inc
市场价: ¥6160.00
美元价: 3696.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
MoreInformation
ProductDetails
SynonymsTTR;ATTR;PALB;TBPA;Prealbumin;Transthyretin
ProductTypeMonoclonalAntibody
Properties
Clone10E1
IsotypeMouseIgG2aκ
Immunogen/AntigenRecombinanthumanproteinpurifiedfromE.coli.
ApplicationWesternBlot(1:2,000)
Immunoprecipitation(3μl)
CrossreactivityHuman
PurityDetailAmmoniumsulfateprecipitation.
FormulationLiquid.HEPESwith0.15MNaCl,0.01%BSA,0.03%sodiumazide,and50%glycerol.
OtherProductDataClickhereforOriginalManufacturerProductDatasheet
Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet.
DeclarationManufacturedbyAbFrontier
ShippingandHandling
ShippingBLUEICE
ShortTermStorage+4°C
LongTermStorage-20°C
Use/StABIlityStableforatleast1yearafterreceiptwhenstoredat-20°C.
Documents
MSDSNo
ProductSpecificationSheet
DatasheetDownloadPDF
Transthyretin(TTR,55kDahomotetramer)isathyroidhormone-bindingproteinthattransportsthyroxine(T4)fromthebloodstreamtothebrain.TTRwasoriginallycalledprealbuminbecauseitranfasterthanalbuminonelectrophoresisgels.TTRisproducedintheliverandcirculatesinthebloodstream,whereitbindsretinolandthyroxine.TTRissuggestedthatplaysanessentialroleinbrainfunction.Theproteinconsistsofaround130aminoacids,whichassembleasahomotetramerthatcontainsaninternalchannelinwhichT4isbound.Withinthiscomplex,T4appearstobetransportedacrosstheblood-brainbarrier,where,inthechoroidplexus,thehormonestimulatesfurthersynthesisoftransthyretin.Theproteinthendiffusesbackintothebloodstream,whereitbindsT4fortransportbacktothebrain.TTRisknowntobeassociatedwiththeamyloiddiseasessenilesystemicamyloidosis(SSA),familialamyloidpolyneuropathy(FAP),andfamilialamyloidcardiomyopathy(FAC).Thyroidhormone-bindingprotein.Probablytransportsthyroxinefromthebloodstreamtothebrain.
ProductReferences
1)PalhaJA.ClinChemLabMed.(2002)vol.40(12):pp.1292-300.(General)
2)HamiltonJA,BensonMD.CellMolLifeSci.(2001)vol.58(10):pp.1491-521.(General)
3)HundE,etal,Neurology.(2001)vol.56(4):pp.431-5.(General)
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。