当前位置：
首页
>
产品中心 >
Functional_antibody >
Adipogen/anti-TRAIL-R3 (human), mAb (HS301)/AG-20B-0024-C100/100 µg
Adipogen/anti-TRAIL-R3 (human), mAb (HS301)/AG-20B-0024-C100/100 µg
商品编号：
AG-20B-0024-C100
品牌：
Adipogen Inc
市场价：
¥7400.00
美元价：
4440.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | TRAILReceptor3;DcR1;TRID;TNFRSF10C;CD263 |
| ProductType | MonoclonalAntibody |
| Properties | |
| Clone | HS301 |
| Isotype | MouseIgG1 |
| Source/Host | Purifiedfromconcentratedhybridomatissueculturesupernatant. |
| Immunogen/Antigen | RecombinanthumanTRAIL-R3(DcR1). |
| Application | FlowCytometry Immunocytochemistry |
| Crossreactivity | Human |
| Specificity | RecognizeshumanTRAIL-R3.Doesnotcross-reactwithhumanTRAIL-R1,-R2or-R4. |
| Purity | ≥95%(SDS-PAGE) |
| PurityDetail | ProteinG-affinitypurified. |
| Concentration | 1mg/ml |
| Formulation | Liquid.InPBScontaining10%glyceroland0.02%sodiumazide. |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Afteropening,preparealiquotsandstoreat-20°C. Avoidfreeze/thawcycles. |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
TRAIL-R3isareceptorforthecytotoxicligandTRAIL.Itlacksacytoplasmicdeathdomainandhenceisnotcapableofinducingapoptosis.ProtectscellsagainstTRAILmediatedapoptosisbycompetingwithTRAIL-R1andR2forbindingtotheligand.
ProductReferences
- TNF-RelatedApoptosis-InducingLigandMediatesTumoricidalActivityofHumanMonocytesStimulatedbyNewcastleDiseaseVirus:B.Washburn,etal.;J.Immunol.170,1814(2003)
- TRAILregulatesnormalerythroidmaturationthroughanERK-dependentpathway:P.Secchiero,etal.;Blood103,517(2004)
- Enhancedcaspase-8recruitmenttoandactivationattheDISCiscriticalforsensitisationofhumanhepatocellularcarcinomacellstoTRAIL-inducedapoptosisbychemotherapeuticdrugs:T.M.Ganten,etal.;CellDeathDiffer.11Suppl1, 86(2004)
- cFLIPLinhibitstumornecrosisfactor-relatedapoptosis-inducingligand-mediatedNF-kappaBactivationatthedeath-inducingsignalingcomplexinhumankeratinocytes:T.Wachter,etal.;J.Biol.Chem.279,52824(2004)
- ResistancetoFasLandtumornecrosisfactor-relatedapoptosis-inducingligand-mediatedapoptosisinSezarysyndromeT-cellsassociatedwithimpaireddeathreceptorandFLICE-inhibitoryproteinexpression:E.Contassot,etal.;Blood111,4780(2008)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
联络我们
