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当前位置: 首页 > 产品中心 > Functional_antibody > Adipogen/anti-TLR9, mAb (ABM1C51) (FITC)/AG-20T-0308F-C100/100 µg
商品详细Adipogen/anti-TLR9, mAb (ABM1C51) (FITC)/AG-20T-0308F-C100/100 µg
Adipogen/anti-TLR9, mAb (ABM1C51) (FITC)/AG-20T-0308F-C100/100 µg
Adipogen/anti-TLR9, mAb (ABM1C51) (FITC)/AG-20T-0308F-C100/100 µg
商品编号: AG-20T-0308F-C100
品牌: Adipogen Inc
市场价: ¥7400.00
美元价: 4440.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
MoreInformation
ProductDetails
SynonymsToll-likeReceptor9;CD289
ProductTypeMonoclonalAntibody
Properties
CloneABM1C51
IsotypeMouseIgG1κ
Immunogen/AntigenRecombinanthumanTLR9protein(aa100-290).
Label/ConjugatesFITC
ApplicationFlowCytometry:(0.5μg/106cells)

Optimalconditionsmustbedeterminedindividuallyforeachapplication.
CrossreactivityHuman
Mouse
SpecificityRecognizeshumanandmouseTLR9.
PurityProteinGpurified.
Concentration0.2mg/ml
FormulationLiquid.In10mMTRIScontaining150mMNaCland0.05%sodiumazide.
AccessionNumberQ9NR96
ShippingandHandling
ShippingBLUEICE
ShortTermStorage+4°C
LongTermStorage+4°C
HandlingAdviceDonotfreeze.
Protectfromlight.
Use/StABIlityStableforatleast6monthsafterreceiptwhenstoredat+4°C.
Documents
MSDSNo
ProductSpecificationSheet
DatasheetDownloadPDF
TLR9(Toll-likeReceptor9)isamemberoftheTLR(Toll-likereceptor)familythatplaysafundamentalroleinpathogenrecognitionandactivationofinnateimmunity.TLR9isexpressedbynumerouscellsoftheimmunesystemsuchasBlymphocytes,monocytes,naturalkiller(NK)cellsandplasmacytoiddendriticcells.Itisexpressedintracellularly,withintheendosomalcompartmentsandfunctionstoalerttheimmunesystemofviralandbacterialinfectionsbybindingtoDNArichinCpGmotifs.Thisnucleotide-sensingTLRisactivatedbyunmethylatedcytidine-phosphate-guanosine(CpG)dinucleotides(alsocalledoligodinucleotides,ODNs),andconsequentlysignalsviaMYD88andTRAF6,leADIngtoNF-κBactivation,cytokinesecretionandtheinflammatoryresponseandeventuallyactivationofaTh1-biasedadaptiveimmuneattack.SpecificTLR9agoNISTshavebeenshowntohavesubstantialantitumoractivity,makingtheTLR9signalingpathwayaninterestingtargetfortherapeuticresearch.
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。