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Adipogen/anti-TLR6 (human), mAb (ABM1B50) (FITC)/AG-20T-0305F-C100/100 µg
Adipogen/anti-TLR6 (human), mAb (ABM1B50) (FITC)/AG-20T-0305F-C100/100 µg
商品编号：
AG-20T-0305F-C100
品牌：
Adipogen Inc
市场价：
¥7400.00
美元价：
4440.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | Toll-likeReceptor6;CD286 |
| ProductType | MonoclonalAntibody |
| Properties | |
| Clone | ABM1B50 |
| Isotype | MouseIgG1κ |
| Immunogen/Antigen | RecombinanthumanTLR6protein(aa280-512). |
| Label/Conjugates | FITC |
| Application | Flowcytometry:(0.5µg/106cells) Optimalconditionsmustbedeterminedindividuallyforeachapplication. |
| Crossreactivity | Human |
| Specificity | RecognizeshumanTLR6. |
| Purity | ProteinGpurified. |
| Concentration | 0.2mg/ml |
| Formulation | Liquid.In10mMTRIScontaining150mMNaCland0.05%sodiumazide. |
| AccessionNumber | Q9Y2C9 |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | +4°C |
| HandlingAdvice | Donotfreeze. Protectfromlight. |
| Use/StABIlity | Stableforatleast6monthsafterreceiptwhenstoredat+4°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
TLR6(Toll-likeReceptor6)isamemberoftheTLR(Toll-likereceptor)familythatplaysafundamentalroleinpathogenrecognitionandactivationofinnateimmunity.TLR6incomplexwithTLR2specificallyrecognizesdiacylatedand,toalesserextent,triacylatedlipopeptidesfromGram-positivebacteriaandfungi.TheactivationclusterTLR2:TLR6:CD14:CD36signalsviaMYD88andTRAF6,leADIngtoNF-κBactivation,cytokinesecretionandtheinflammatoryresponse.IncomplexwithTLR2recognizesMALP-2,STF,PSMandOspA-L,aswell.Inresponsetooxidizedlow-densitylipoprotein(oxLDL)oramyloid-β42,TLR6formsaheterodimerwithTLR4.ThiscomplexrapidlyinternalizesandtriggersinflammatoryresponsesthroughtheNF-κB-dependentMYD88signalingorviaTICAM1signalingpathways.Thecomplexpromotessterileinflammationinmonocytes/macrophages.TLR6hasemergedasthemostpotentactivatorforZNPs(ZincOxideNanoparticles)-inducedinflammatoryresponses.Variouspolymorphismhavebeenassociatedwithinflammatoryandtumorpathologies.
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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