Adipogen/anti-TLR2, mAb (ABM3A87)/AG-20T-0300-C100/100 µg
商品编号：
AG-20T-0300-C100
品牌：
Adipogen Inc
市场价：
¥7200.00
美元价：
4320.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | Toll-likeReceptor2;CD282;Toll/Interleukin-1Receptor-likeProtein4;TIL4 |
| ProductType | MonoclonalAntibody |
| Properties | |
| Clone | ABM3A87 |
| Isotype | MouseIgG1κ |
| Immunogen/Antigen | RecombinanthumanTLR2protein(aa180-420). |
| Application | FlowCytometry:(0.5μg/106cells) Immunohistochemistry:(5μg/ml;paraffinsections) WesternBlot:(2-4μg/ml) Optimalconditionsmustbedeterminedindividuallyforeachapplication. |
| Crossreactivity | Human Mouse |
| Specificity | RecognizeshumanandmouseTLR2. |
| Purity | ProteinGpurified. |
| Concentration | 0.5mg/ml |
| Formulation | Liquid.InPBScontaining0.05%BSAand0.05%sodiumazide. |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Afteropening,preparealiquotsandstoreat-20°C. Avoidfreeze/thawcycles. |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. Stableforatleast6monthsafterreceiptwhenstoredat+4°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
TLR2(Toll-likeReceptor2)isamemberoftheTLR(Toll-likereceptor)familythatplaysafundamentalroleinpathogenrecognitionandactivationofinnateimmunity.TLR2actsviaMYD88andTRAF6,leADIngtoNF-κBactivation,cytokinesecretionandtheinflammatoryresponse.TLR2residesontheplasmamembranewhereitrespondstolipid-containingpathogen-associatedmolecularpatterns(PAMPs),suchaslipoteichoicacidanddi-andtri-acylatedcysteine-containinglipopeptides.ItdoesthisbyformingdimericcomplexeswitheitherTLR1orTLR6,whichconsequentlyistheinitialstepinacascadeofeventsleadingtosignificantinnateimmuneresponses,developmentofadaptiveimmunitytopathogensandprotectionfromimmunesequelaerelatedtoinfectionswiththesepathogens.TLR2alsointeractswithalargenumberofnon-TLRmoleculessuchasLY96(MD-2),allowingforrecognitionofagreatnumberandvarietyofPAMPs(pathogen-associatedmolecularpatterns).TLR2expressionhasbeendetectedinimmunecells,endothelialandepithelialcells.
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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