Adipogen/anti-TCPTP, mAb (T25-AF3B7)/YIF-LF-MA0344/100 µl
商品编号：
YIF-LF-MA0344
品牌：
Adipogen Inc
市场价：
¥6160.00
美元价：
3696.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Details | |
|---|---|
| Synonyms | PTPT; TCPTP; PTPN2; EC=3.1.3.48; T-Cell Protein-Tyrosine Phosphatase; Tyrosine-Protein Phosphatase Non-Receptor Type 2 |
| Product Type | Monoclonal Antibody |
| Properties | |
| Clone | T25-AF3B7 |
| Isotype | Mouse IgG2b κ |
| Immunogen/Antigen | Recombinant human protein purified from E. coli. |
| Application |
ELISA Western Blot (1:2,000) |
| Crossreactivity | Human |
| Purity Detail | Ammonium sulfate precipitation. |
| Formulation | Liquid. HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| Declaration | Manufactured by AbFrontier |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Documents | |
| MSDS | No |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
T cell protein tyrosine phosphatase (TCPTP), also known as PTPT and PTPN2, is an enzyme that removes phosphate groups covalently attached to tyrosine residues in proteins. TCPTP is ubiquitously expressed with particularly high expression in hematopoietic tissues and exists as two forms: an endoplasmic reticulum-targeted 48-kDa form (TC48) and a nuclear 45-kDa form (TC45). Although targeted to the nucleus, TC45 can exit in response to specific stimuli to dephosphorylate cytoplasmic substrates. TC-PTP is a negative regulator of the Jak/Stat cytokine signaling pathway. TCPTP is the PTP most closely related to PTP1B, with 72% sequence identity and 86% similarity in the catalytic domain.
Product References
1) Galic S et al., (2003) Mol Cell Biol 23(6):2096-108. (General)
2) Bourdeau A et al., (2007) Blood 109(10):4220-8. (General)
3) Doody KM et al., (2009) Immunol Rev 228(1):325-41. (General)
2) Bourdeau A et al., (2007) Blood 109(10):4220-8. (General)
3) Doody KM et al., (2009) Immunol Rev 228(1):325-41. (General)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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