Adipogen/anti-TAB1, mAb (2D3)/YIF-LF-MA0196/100 µl
商品编号：
YIF-LF-MA0196
品牌：
Adipogen Inc
市场价：
¥6160.00
美元价：
3696.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | TAB1;MAP3K7IP1;TAK1-bindingProtein1;TGF-β-activatedKinase1-bindingProtein1;TGF-β-activatedKinase1andMAP3K7-bindingProtein1;Mitogen-activatedProteinKinaseKinaseKinase7-interactingProtein1 |
| ProductType | MonoclonalAntibody |
| Properties | |
| Clone | 2D3 |
| Isotype | MouseIgG2aκ |
| Immunogen/Antigen | RecombinanthumanHis-TAB1(1~300)proteinpurifiedfromE.coli. |
| Application | ELISA WesternBlot(1:5,000~10,000) |
| Crossreactivity | Human Mouse Rat |
| PurityDetail | Ammoniumsulfateprecipitation. |
| Formulation | Liquid.HEPESwith0.15MNaCl,0.01%BSA,0.03%sodiumazide,and50%glycerol. |
| OtherProductData | ClickhereforOriginalManufacturerProductDatasheet Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet. |
| Declaration | ManufacturedbyAbFrontier |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
TAK1(transforminggrowthfactor-β-activatedkinase1)isaMAPKKKactivatedbyTGF-β,orthepro-inflammatorycytokinesTNF(tumournecrosisfactor)andIL-1(interleukin-1),orbacterialLPS(lipopolysacchar-ide).Itplaysakeyroleinswitchingonseveralpro-inflammatorysignalingpathways,includingthosethatactivatetheMAPKs(mitogen-activatedproteinkinases),termedp38αMAPK,JNK1/2(c-JunN-terminalkinase1/2)andERK1/2(extracellular-signal-regulatedkinase1/2),aswellasthetranscriptionfactorNFκB(nuclearfactorκB).TAB1(TAK1-bindingprotein1)isoneoftheregulatorysubunitsofTAK1andplaysaroleasanactivatorofTAK1inresponsetostimulationofΤGF-β.TAB-1canalsomediateMKK-independentp38kinase.Recently,inductionofp38autophosphorylationandconsequentkinaseactivationbyTAB1expressioninculturedneonatalcardiomyocyteshavebeenreported.MaybeanimportantsignalingintermediatebetweenTGFBreceptorsandMAP3K7/TAK1.Mayplayanimportantroleinmammalianembryogenesis.
ProductReferences
1)SunP.etal.,(2007)Cell.128:295-308.(General)
2)NewL.etal.,(1998)EMBOJ.17:3372-3384.(General)
2)NewL.etal.,(1998)EMBOJ.17:3372-3384.(General)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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