脂肪原/抗-SPRR3（人），pAb（4A）/AG-25B-0003-R100/100µl
商品编号：
AG-25B-0003-R100
品牌：
Adipogen Inc
市场价：
¥7000.00
美元价：
4200.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | SmallProline-richProtein3 |
| ProductType | PolyclonalAntibody |
| Properties | |
| Source/Host | Rabbit |
| Immunogen/Antigen | Syntheticpeptidecorrespondingtoaa115-130(I115KVPDQGFIKFPEPGA130)ofhumanSPRR3. |
| Application | Immunocytochemistry: Immunohistochemistry:(paraffinsections) WesternBlot:(1:2"000-1:4"000) |
| Crossreactivity | Human |
| Specificity | RecognizeshumanSPRR3.Doesnotcross-reactwithSPRR1orSPRR2. |
| Formulation | Liquid.Neatserumcontaining0.02%sodiumazide. |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Afteropening,preparealiquotsandstoreat-20°C. Avoidfreeze/thawcycles. |
| Use/StABIlity | Formaximumproductrecoveryafterthawing,centrifugethevialbeforeopeningthecap. Stableforatleast1yearafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
Theformationofthecornified(CE)envelopeduringthelatestagesofepidermaldifferentiationisessentialforepidermalbarrierfunctionandprotectsthebodyagainstenvironmentalattackandwaterloss.Formationofthecornifiedenvelopeinvolvesthereplacementoftheplasmamembranebycross-linkageofprecursorproteinssuchasloricrin,involucrinandsmallprolinerichproteins(SPRR).SPRRgenesconstituteamultigenefamilyclusteredwithintheepidermaldifferentiationcomplexonchromosome1q21.ThisclustercontainstwoSPRR1genes,sevenSPRR2genesandasingleSPRR3gene.SPRRgeneproductsaredifferentiallyexpressedinvivoandinvitrosuggestingthattheSPRRmultigenefamilyevolvedtoprovidehighlyspecializedcornifiedenvelopeprecursorproteinsinstratifiedepithelia.SPRR2ismainlyexpressedininterfollicularepidermis.
ProductReferences
- Thesmallproline-richproteinsconstituteamultigenefamilyofdifferentiallyregulatedcornifiedcellenvelopeprecursorproteins:D.Hohl,etal.;J.Invest.Dermatol.104,902(1995)
- Expressionofsmallprolinerichproteinsinneoplasticandinflammatoryskindiseases:M.DeHeller-Milev,etal.;Br.J.Dermatol.143,733(2000)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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