Adipogen/anti-SOD1, pAb/YIF-LF-PA0213/100 µl
商品编号：
YIF-LF-PA0213
品牌：
Adipogen Inc
市场价：
¥6160.00
美元价：
3696.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | SOD1;hSod1;EC=1.15.1.1;SuperoxideDismutase1;SuperoxideDismutase[Cu-Zn] |
| ProductType | PolyclonalAntibody |
| Properties | |
| Immunogen/Antigen | RecombinanthumanproteinpurifiedfromE.coli. |
| Application | WesternBlot(1:2,000) |
| Crossreactivity | Human Mouse Rat |
| PurityDetail | ProteinApurified. |
| Concentration | 0.5mg/ml |
| Formulation | Liquid.HEPESwith0.15MNaCl,0.01%BSA,0.03%sodiumazide,and50%glycerol. |
| OtherProductData | ClickhereforOriginalManufacturerProductDatasheet Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet. |
| Declaration | ManufacturedbyAbFrontier |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
Superoxidedismutase(SOD)isanantioxidantenzymeinvolvedinthedefensesystemagainstreactiveoxygenspecies(ROS).SODcatalyzesthedismutationreactionofsuperoxiderADIcalanion(O2-)hydrogenperoxide,whichisthencatalyzedtoinnocuousO2andH2Obyglutathioneperoxidaseandcatalase.SeveralclassesofSODhavebeenidentified.Theseincludeintracellularcopper,zincSOD(Cu,Zn-SOD/SOD-1),mitochondrialmanganeseSOD(Mn-SOD/SOD-2)andextracellularCu,Zn-SOD(EC-SOD/SOD-3)(1).SOD-1isfoundinalleukaryoticspeciesasahomodimeric32kDaenzymecontainingoneeachofCuandZnionpersubunit(2).Themanganesecontaining80kDatetramericenzymeSOD2,islocatedinthemitochondrialmatrixincloseproximitytoaprimaryendogenoussourceofsuperoxide,themitochondrialrespiratorychain(3).SOD-3isaheparin-bindingmultimerofdisulfide-linkeddimers,primarilyexpressedinhumanlungs,vesselwallsandairways(4).SOD-4isacopperchaperoneforsuperoxidedismutase(CCS),whichspecificallydeliversCutocopper/zincsuperoxidedismutase.CCSmayactivatecopper/zincsuperoxidedismutasethroughdirectinsertionoftheCucofactor.DestroysradicalswhicharenormallyproducedwithinthecellsandwhicharetoxictoBIOLOGicalsystems.
ProductReferences
1)Kuninaka,S.etal.(2000)Br.J.Cancer.83,928-934.(General)
2)Strange,R.W.etal.(2003)J.Mol.Biol.328,877-891.(General)
3)Weisiger,R.A.,andFridovich,I.(1973)J.Biol.Chem.248,3582-3592.(General)
4)Enghild,J.J.etal.(1999)BiochemJ.317,51-57.(General)
2)Strange,R.W.etal.(2003)J.Mol.Biol.328,877-891.(General)
3)Weisiger,R.A.,andFridovich,I.(1973)J.Biol.Chem.248,3582-3592.(General)
4)Enghild,J.J.etal.(1999)BiochemJ.317,51-57.(General)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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