![Adipogen/anti-Slc7a8 [Lat2], pAb/AG-25T-0120-C100/100 µg](https://www.ebiomall.cn/images/adipogen/ag-25t-0120_western-blot_1.png)
Adipogen/anti-Slc7a8 [Lat2], pAb/AG-25T-0120-C100/100 µg
商品编号：
AG-25T-0120-C100
品牌：
Adipogen Inc
市场价：
¥9200.00
美元价：
5520.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | SoluteCarrierFamily7Member8;Lat2;L-typeAminoAcidTransporter2;LargeNeutralAminoAcidsTransporterSmallSubunit2 |
| ProductType | PolyclonalAntibody |
| Properties | |
| Source/Host | Rabbit |
| Immunogen/Antigen | SyntheticpeptidecorrespondingtoapartialsequenceofmouseSlc7a8(Q9QXW9). |
| Application | WesternBlot:(1:1"000;0.5μg/ml) Immunohistochemistry:(1:250;2μg/ml) Optimalconditionsmustbedeterminedindividuallyforeachapplication. |
| Crossreactivity | Human Mouse |
| Specificity | RecognizesmouseandhumanSlc7a8.Otherspeciesnottested. Detectsa~50kDaSlc7a8bandinwildtypemousebrain,kidney,jejunum,ileumandothertissues,whichisabsentinknock-outanimals.Insometissuestheantibodydetectsanadditionalunknown38kDaband. |
| Purity | Antigenaffinitypurified. |
| Formulation | Liquid.InPBScontaining1mg/mlBSAand0.02%sodiumazide. |
| OtherProductData | UniProtIDQ9QXW9:Slc7a8(mouse) |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Avoidfreeze/thawcycles. |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
L-typeaminoacidtransporter(LAT)familymembersareNa(+)-independenttransporters,whichdeliverneutralaminoacidsintocells.ThefourLATs,LAT1(SLC7A5),LAT2(SLC7A8),LAT3(SLC43A1)andLAT4(SLC43A2)areresponsIBLeforthemajorityofcellularleucineuptake.TheyshowincreasedexpressioninmanycancersandarecriticalforcontrolofproteintranslationandcellgrowththroughthemTORC1pathway.Theincreasedtransporterexpressionobservedincancersisregulatedbytranscriptionalpathwayssuchashormonereceptors,c-mycandnutrientstarvationresponses.
ProductReferences
- Neuronal3",3,5-triiodothyronine(T3)uptakeandbehavioralphenotypeofmicedeficientinMct8,theneuronalT3transportermutatedinAllan-Herndon-Dudleysyndrome:E.K.Wirth,etal.;J.Neurosci.29,9439(2009)
- Aminoaciduria,butnormalthyroidhormonelevelsandsignalling,inmicelackingtheaminoacidandthyroidhormonetransporterSlc7a8:D.Braun,etal.;Biochem.J.439,249(2011)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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