Adipogen/anti-RIP2, mAb (AF28D3)/YIF-LF-MA0288/100 µl
商品编号：
YIF-LF-MA0288
品牌：
Adipogen Inc
市场价：
¥6160.00
美元价：
3696.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | RIP-2;RIPK2;CARDIAK;EC=2.7.11.1;EC=2.7.10.2;Tyrosine-ProteinKinaseRIPK2;Receptor-interactingProtein2;RIP-like-interactingCLARPKinase;CARD-containingIL-1βICE-Kinase |
| ProductType | MonoclonalAntibody |
| Properties | |
| Clone | AF28D3 |
| Isotype | MouseIgG1κ |
| Immunogen/Antigen | RecombinanthumanHis-RIP2proteinpurifiedfromE.coli. |
| Application | ELISA WesternBlot(1:2,000) Immunoprecipitation(3μl) |
| Crossreactivity | Human Mouse Rat |
| PurityDetail | Ammoniumsulfateprecipitation. |
| Formulation | Liquid.HEPESwith0.15MNaCl,0.01%BSA,0.03%sodiumazide,and50%glycerol. |
| OtherProductData | ClickhereforOriginalManufacturerProductDatasheet Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet. |
| Declaration | ManufacturedbyAbFrontier |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
TheRIP(receptor-interactingprotein)familyofserine/Threoninekinases(RIP-1,2,3,4,5,6,7)arecrucialregulatorsofcellsurvivalandcelldeaththatcantriggerpro-survival,inflammatoryandimmuneresponsesviatheactivationoftranscriptionfactors(NF-κBandAP-1)anddeath-inducingprograms.RIP2(alsoknownasRICK,CARDIAK,CCKandRipk2)transducessignalsfromreceptorsofbothimmuneresponses.RIP2carriesaCARDatitsC-terminal,whichisessentialforNF-κBactivation.RIP2isacriticaldownstreammediatorofNod1andNod2signaling.OverexpressionofRIP2resultsintheactivationof,inadditiontoNF-κB,theMAPKsJNKandERK2,requiringitskinaseactivitytoactivateERK2,butnotJNK.Activatespro-caspase-1andpro-caspase-8.PotentiatesCASP8-mediatedapoptosis.ActivatesNF-κB.
ProductReferences
1)KobayashiKetal.,(2002)Nature416,194-199(General)
2)HasegawaM,(2008)EMBO27,373–383(General)
3)MeylanEandTschoppJ,(2005)TRENDSinBiochemSciences30:151-159(General)
2)HasegawaM,(2008)EMBO27,373–383(General)
3)MeylanEandTschoppJ,(2005)TRENDSinBiochemSciences30:151-159(General)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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