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Adipogen/anti-PSD-95 (palmitoylated), mAb (rec.) (PF11)/AG-27B-0021-C100/100 µg
Adipogen/anti-PSD-95 (palmitoylated), mAb (rec.) (PF11)/AG-27B-0021-C100/100 µg
商品编号：
AG-27B-0021-C100
品牌：
Adipogen Inc
市场价：
¥7600.00
美元价：
4560.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | PSD95;DisksLargeHomolog4;DLG4;PostsynapticDensityProtein95;Synapse-associatedProtein90;SAP90 |
| ProductType | RecombinantAntibody |
| Properties | |
| Clone | PF11 |
| Isotype | HumanIgG2 |
| Source/Host | HEK293cells |
| Immunogen/Antigen | PalmitoylatedPSD-95. |
| Application | Immunocytochemistry:1/1000dilution(fixedwithmethanol) Immunohistochemistry:1/500dilution(fixedwithacetone;doesnotworkwithparaformaldehyde) |
| Crossreactivity | Human Mouse Rat |
| Specificity | Recognizeshuman,mouseandratpalmitoylatedPSD-95. |
| Purity | ≥95%(SDS-PAGE) |
| PurityDetail | ProteinA-affinitypurified. |
| Concentration | 0.5mg/ml |
| Formulation | Liquid.InPBScontaining10%glycerol. |
| OtherProductData | anti-PSD95Palmitoylated,mAb(rec.)(PF11)iscomposedofhumanvariableregions(VHandVL)(&lamBDa;-chain)ofimmunoglobulinfusedtothehumanlgG2Fcdomain. |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Afteropening,preparealiquotsandstoreat-20°C. Avoidfreeze/thawcycles. |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
PSD-95isamemberofproteinslocatedataspecializedpostsynapticmembraneregion,calledthepostsynapticdensity(PSD).PSD-95isthemostabundantscaffoldproteinspecificallyenrichedinthePSD.ItcontainsthreePDZdomains,anSH3domainandaguanylatekinase(GuK)-likedomain.ThroughitsPDZdomains,PSD-95assemblesvarioussynapticcomponentsatthePSDincludingintracellularsignalingmolecules(e.g.SynGAPandkalirin-7),ionchannels(e.g.stargazin/AMPAreceptors[AMPARs]andNMDAreceptors)andcelladhesionmolecules(e.g.neuroligin).PSD-95playsaprimaryroleinsynapticdevelopmentandmaturationandisregulatedbypalmitoylationatitsN-terminalcysteineresiduesleADIngtoitspostsynaptictargeting.PalmitoylationofPSD-95istriggeredbyDHHC2,aplasmamembrane-insertedpalmitoylatingenzyme.PalmitoylatedPSD-95isalmostexclusivelylocalizedatexcitatorysynapsesinneurons.
ProductReferences
- Localpalmitoylationcyclesdefineactivity-regulatedpostsynapticsubdomains:Y.Fukata,etal.;J.CellBiol.202,145(2013)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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