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Adipogen/anti-Protein Tyrosine Phosphatase 1B, mAb (3A7)/YIF-LF-MA0051/100 µl
Adipogen/anti-Protein Tyrosine Phosphatase 1B, mAb (3A7)/YIF-LF-MA0051/100 µl
商品编号:
YIF-LF-MA0051
品牌:
Adipogen Inc
市场价:
¥6160.00
美元价:
3696.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | PTP1B;PTPN1;PTP-1B;EC=3.1.3.48;Protein-TyrosinePhosphatase1B;Tyrosine-ProteinPhosphataseNon-ReceptorType1 |
| ProductType | MonoclonalAntibody |
| Properties | |
| Clone | 3A7 |
| Isotype | MouseIgG2aκ |
| Immunogen/Antigen | RecombinanthumanproteinpurifiedfromE.coli. |
| Application | WesternBlot(1:2,000) |
| Crossreactivity | Human |
| PurityDetail | Ammoniumsulfateprecipitation. |
| Formulation | Liquid.HEPESwith0.15MNaCl,0.01%BSA,0.03%sodiumazide,and50%glycerol. |
| OtherProductData | ClickhereforOriginalManufacturerProductDatasheet Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet. |
| Declaration | ManufacturedbyAbFrontier |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
Invivo,tyrosinephosphorylationisreversIBLeanddynamicandthephosphorylationstatesaregovernedbytheopposingactivitesofproteintyrosinekinases(PTKs)andproteintyrosinephosphatases(PTPs).PTPsareinvolvedincontrollingofdiversearrayofcellularprocess.Theyarelarge(~100)andstructurallydiversefamilyofenzymes.PTPscontainoneortwocatalyticdomainswhichisapproximately280residuesandarecharacterizedbytheexistenceofthesignaturemotifHC(X)5R.TheCysandArgresiduesinthismotifhaveessentialfunctionsforcatalyticactivity.PTPsregulatecellgrowthandmetabolism,withspecialemphasisonitsabilitytoregulateintegrin,growthfactor,andcytokinesignaling.MayplayanimportantroleinCKII-andp60c-src-inducedsignaltransductioncascades
ProductReferences
1)Tonks,N.K.(2003)FEBSLett.546(1),140-148.(General)
2)Zhang,Z.Y.(2002)Annu.Rev.Pharmacol.Toxicol.42,209-234.(General)
3)Neel,B.G.andTonks,N.K.(1997)Curr.Opin.Cell.Biol.9,193-204.(General)
2)Zhang,Z.Y.(2002)Annu.Rev.Pharmacol.Toxicol.42,209-234.(General)
3)Neel,B.G.andTonks,N.K.(1997)Curr.Opin.Cell.Biol.9,193-204.(General)
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。
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