脂肪原/抗波多普兰（小鼠），单克隆抗体（RTD4E10）/AG-20T-0101-C100/100µg
商品编号：
AG-20T-0101-C100
品牌：
Adipogen Inc
市场价：
¥9800.00
美元价：
5880.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Details | |
|---|---|
| Synonyms | Glycoprotein 36; PA2.26 Antigen; Aggrus |
| Product Type | Monoclonal Antibody |
| Properties | |
| Clone | RTD4E10 |
| Isotype | Hamster IgG |
| Immunogen/Antigen | Murine thymic stromal cell line. |
| Application |
Immunohistochemistry: (1-10μg/ml) Immunoprecipitation: (2-10μg/ml) Western Blot: (1-5μg/ml) ELISA: (functional ELISA) Optimal conditions must be determined individually for each application. |
| Crossreactivity | Mouse |
| Specificity | Recognizes mouse podoplanin. Does not cross-react with human podoplanin. |
| Purity | Protein G purified. |
| Purity Detail | Protein G-affinity purified. |
| Formulation | Lyophilized. |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute with sterile water to a concentration of 0.1-1.0mg/ml. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 6 months after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells and numerous tumors, including colorectal tumors, squamous cell carcinomas, testicular seminoma and brain tumors. Podoplanin is the ligand for C-type lectin-like receptor 2 (CLEC-2). Their association is dependent on sialic acid on O-glycans of podoplanin. Through its association with CLEC-2, podoplanin induces platelet aggregation and tumor metastasis. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth.
Product References
- Mouse lungs contains endothelial progenitors with high capacity to form blood and lymphatic vessels: J. Schniedermann, et al.; BMC Cell Biology 11, 1471 (2010)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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