Adipogen/anti-PLC γ, mAb (2B1)/YIF-LF-MA0050/100 µl
商品编号:
YIF-LF-MA0050
品牌:
Adipogen Inc
市场价:
¥6160.00
美元价:
3696.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | PLC1;PLCG1;PLC-II;PLC-148;EC=3.1.4.11;PLC-γ-1;PhospholipaseC-II;PhospholipaseC-γ-1;PhosphoinositidePhospholipaseC-γ-1;1-Phosphatidylinositol4;5-BisphosphatePhosphodiEsteraseγ-1 |
| ProductType | MonoclonalAntibody |
| Properties | |
| Clone | 2B1 |
| Isotype | MouseIgG2aκ |
| Immunogen/Antigen | RecombinanthumanproteinpurifiedfromE.coli. |
| Application | WesternBlot(1:2,000) Immunoprecipitation(1μl) |
| Crossreactivity | Human Mouse Rat |
| PurityDetail | Ammoniumsulfateprecipitation. |
| Formulation | Liquid.HEPESwith0.15MNaCl,0.01%BSA,0.03%sodiumazide,and50%glycerol. |
| OtherProductData | ClickhereforOriginalManufacturerProductDatasheet Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet. |
| Declaration | ManufacturedbyAbFrontier |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
ThemammalianPhospholipaseC(PLC)familyhastwocloselyrelatedproteins,PLC1andPLC2.ThePLCisozymeshavethecorestructuredomainsandauniquearrayofdomainscontaininganadditionalPHdomain,twoSH2domainsandoneSH3domain.Inresponsetoextracellularstimuli,suchashormonesandgrowthfactors,receptortyrosinekinases(RTKs)phosphorylateandactivatePLCγ.ActivatedPLCcatalyzeshydrolysisofphosphatidylinositol4,5-bisphosphate(PIP2)toproducethemetabolicsecondmessengermoleculesinositol1,4,5-triphosphate(IP3)anddiacylglycerol(DAG).PLC-γisamajorsubstrateforheparin-bindinggrowthfactor1(acidicfibroblastgrowthfactor)-activatedtyrosinekinase.
ProductReferences
1)Katan,M.(1998)Biochim.Biophys.Acta,1436,5-17.(General)
2)Singer,W.D.etal.(1997)Annu.Rev.Biochem.66,475-509.(General)
3)Wang,Z.etal.(1998)Mol.Cell.Biol.18,590-597.(General)
2)Singer,W.D.etal.(1997)Annu.Rev.Biochem.66,475-509.(General)
3)Wang,Z.etal.(1998)Mol.Cell.Biol.18,590-597.(General)
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。
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