当前位置：
首页
>
产品中心 >
Functional_antibody >
Adipogen/anti-Phospho-Stat3 (Y705), pAb/YIF-LF-PA0071/100 µl
Adipogen/anti-Phospho-Stat3 (Y705), pAb/YIF-LF-PA0071/100 µl
商品编号：
YIF-LF-PA0071
品牌：
Adipogen Inc
市场价：
¥6160.00
美元价：
3696.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | APRF;STAT3;Acute-phaseresponseFactor;SignalTransducerandActivatorofTranscription3 |
| ProductType | PolyclonalAntibody |
| Properties | |
| Immunogen/Antigen | Syntheticpeptide. |
| Application | WesternBlot(1:2,000) |
| Crossreactivity | Human |
| PurityDetail | ProteinApurified. |
| Formulation | Liquid.HEPESwith0.15MNaCl,0.01%BSA,0.03%sodiumazide,and50%glycerol. |
| OtherProductData | ClickhereforOriginalManufacturerProductDatasheet Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet. |
| Declaration | ManufacturedbyAbFrontier |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
Signaltransducerandactivatoroftranscription(STAT),namedaftertheirdualrole,arelatentcytoplasmictranscriptionfactorsthatmediatevariousBIOLOGicalresponses.TheactivationofSTATproteinsislargelymediatedbyphosphorylationofC-terminaltransactivationdomainthroughJanuskinases(JAKs)andmitogen-activatedproteinkinases(MAPKs),whichallowstheactivatedSTATstodimerizeandtotranslocateintothenucleus.Bymodulatingtargetgeneexpression,STATproteinsplayanimportantroleinmediatingabroadrangeofbiologicalprocessessuchascellproliferation,survival,apoptosis,anddifferentiation.SevenmammalianmembersoftheSTATfamilyareknown(STAT1,2,3,4,5a,5b,and6)andtheyallsharecommonfeaturesandstructure.STAT3isactivatedbygrowthfactorsandoncogenickinaseswhereitmediatestranscriptionalactivationofgenesencodingapoptosisinhibitors,cell-cycleregulatorsandinducersofangiogenesis.Transcriptionfactorthatbindstotheinterleukin-6(IL-6)-responsiveelementsidentifiedinthepromotersofvariousacute-phaseproteingenes.ActivatedbyIL31throughIL31RA.
ProductReferences
1)AggarwalBB,etal,AnnNYAcadSci.2006;vol.1091:p.151-69.(General)
2)GaoSP,BrombergJF.SciSTKE.2006;vol.2006(343):pe30.(General)
3)InghiramiG,etal,CellCycle.2005;vol.4(9):p.1131-3.(General)
4)JingN,TweardyDJ.AnticancerDrugs.2005;vol.16(6):p.601-7.(General)
2)GaoSP,BrombergJF.SciSTKE.2006;vol.2006(343):pe30.(General)
3)InghiramiG,etal,CellCycle.2005;vol.4(9):p.1131-3.(General)
4)JingN,TweardyDJ.AnticancerDrugs.2005;vol.16(6):p.601-7.(General)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
联络我们
