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当前位置: 首页 > 产品中心 > Functional_antibody > Adipogen/anti-p23 (human), mAb (JJ6)/AG-20T-0203-C050/50 µg
商品详细Adipogen/anti-p23 (human), mAb (JJ6)/AG-20T-0203-C050/50 µg
Adipogen/anti-p23 (human), mAb (JJ6)/AG-20T-0203-C050/50 µg
Adipogen/anti-p23 (human), mAb (JJ6)/AG-20T-0203-C050/50 µg
商品编号: AG-20T-0203-C050
品牌: Adipogen Inc
市场价: ¥5160.00
美元价: 3096.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
MoreInformation
ProductDetails
SynonymsProstaglandinESynthase3;CPGES;PTGES3;TEBP;Hsp90Co-chaperone;ProgesteroneReceptorComplexp23;Telomerase-bindingProteinp23
ProductTypeMonoclonalAntibody
Properties
CloneJJ6
IsotypeMouseIgG1
Immunogen/AntigenRecombinantproteincorrespondingtofulllengthhumanPTGES3.
ApplicationWesternBlot(1:2000)
CrossreactivityHuman
SpecificityRecognizeshumanp23.
FormulationLiquid.InPBSpH7.4,50%glycerol,0.09%sodiumazide.
DeclarationManufacturedbyBostonBiochem
ShippingandHandling
ShippingBLUEICE
ShortTermStorage+4°C
LongTermStorage-20°C
HandlingAdviceAliquottoavoidfreeze/thawcycles.
Use/StABIlityStableforatleast1yearafterreceiptwhenstoredat-20°C.
Documents
MSDSNo
ProductSpecificationSheet
DatasheetDownloadPDF
ProstaglandinESynthase3(alsoknownasCytosolicprostaglandinE2synthase,HSP90co-chaperone,Progesteronereceptorcomplexp23,Telomerase-bindingproteinp23,orp23)isaglutathione-dependentenzymefoundinthecyclooxygenase-1-mediatedPGE2biosyntheticpathway.Thisproteinishighlyconservedineukaryotesandinhumansitisexpressedinmosttissuesotherthanstriatedmuscle.Throughitsprostaglandinsynthaseactivity,p23contributestotheproductionofprostaglandinE2andhasaroleinmaintenanceoftissuehomeostasis.Inadditiontoitscatalyticactivityintheprostaglandinbiosynthesispathway,p23servesasaco-chaperonetoHSP90(HeatShockProtein90)invariousBIOLOGicalfunctions.Thep23/HSP90complexisrequiredforefficienttelomeraseassemblyinvitroandinvivo.Ithasalsobeendemonstratedthatp23andHSP90localizetogenomicresponseelementsinahormone-dependentmanner,andmaypromotedisassemblyoftranscriptionalregulatorycomplexesinresponsetochangesincellularsignalingpathways.p23proteinisup-regulatedinseveralcancers,notablybreastcancer.
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。