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Adipogen/anti-OX40L (human), mAb (rec.) (blocking) (R4930) (preservative free)/AG-27B-6001PF-C100/100 µg
Adipogen/anti-OX40L (human), mAb (rec.) (blocking) (R4930) (preservative free)/AG-27B-6001PF-C100/100 µg
商品编号:
AG-27B-6001PF-C100
品牌:
Adipogen Inc
市场价:
¥7600.00
美元价:
4560.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | CD252;CD134L;OX40Ligand;TNFSF4;TumorNecrosisFactorSuperfamilyMember4;TAXTranscriptionally-activatedGlycoprotein1;TXGP1;gp34 |
| ProductType | RecombinantAntibody |
| Properties | |
| Clone | R4930 |
| Isotype | HumanIgG1κ |
| Source/Host | CHOcells |
| Immunogen/Antigen | RecombinanthumanOX40L. |
| Label/Conjugates | PreservativeFree |
| Application | FlowCytometry:1µg/ml FunctionalApplication(Blocking):Bindstotheco-stimulatoryhumanOX40LinhibitingitsinteractionwithOX40invitroandinvivo. Optimalconditionsshouldbedeterminedindividuallyforeachapplication. |
| Crossreactivity | Human |
| Specificity | RecognizeshumanOX40L. |
| Purity | ≥95%(SDS-PAGE) |
| PurityDetail | ProteinA-affinitypurified. |
| EndotoxinContent | <0.001eu mu;g="">0.001eu> |
| Concentration | 1mg/ml |
| Formulation | Liquid.InPBS. |
| AccessionNumber | UniProtIDP23510 |
| OtherProductData | ThisantibodyisabiosimilargenericallycalledOxelumab(CAS1186098-83-8)andoriginallydevelopedbyGenentech.OxelumabisaOX40ligandblockerdesignedforthepreventionofallergen-inducedairwayinflammationinadultswithmildasthma.Potentiallyotherapplicationareasaretransplantationandautoimmunityresearchorprotectionagainstinflammation-drivenfibrosis. |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Avoidfreeze/thawcycles. |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. Stableforatleast3monthsafterreceiptwhenstoredat+4°C. |
| Documents | |
| MSDS | DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
OX40L[CD252;CD134L]isamembrane-expressedcytokinethatbelongstotheTNFligandfamily.ItactsascostimulatorthroughinteractionwithitsligandOX40onTcells,stimulatingTcellactivation,proliferationandcytokineproduction.OX40LisexpressedonantigenpresentingcellsincludingBcells,dendriticcells,mastcellsandendothelium.
ProductReferences
- InvivoblockadeofOX40ligandinhibitsthymicstromallymphopoietindrivenatopicinflammation:D.Seshasayee,etal.;J.Clin.Invest.117,3868(2007)
- Monoclonalantibodiesforthetreatmentofasthma:M.C.Catley,etal.;Pharm.Ther.132,333(2011)
- OX40Lblockadeandallergen-inducedairwayresponsesinsubjectswithmildasthma:G.M.Gauvreau,etal.;Clin.Exp.Allergy44,29(2014)
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。
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