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当前位置: 首页 > 产品中心 > Functional_antibody > Adipogen/anti-OX40L (human), mAb (rec.) (blocking) (R4930) (preservative free)/AG-27B-6001PF-C100/100 µg
商品详细Adipogen/anti-OX40L (human), mAb (rec.) (blocking) (R4930) (preservative free)/AG-27B-6001PF-C100/100 µg
Adipogen/anti-OX40L (human), mAb (rec.) (blocking) (R4930) (preservative free)/AG-27B-6001PF-C100/100 µg
Adipogen/anti-OX40L (human), mAb (rec.) (blocking) (R4930) (preservative free)/AG-27B-6001PF-C100/100 µg
商品编号: AG-27B-6001PF-C100
品牌: Adipogen Inc
市场价: ¥7600.00
美元价: 4560.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
MoreInformation
ProductDetails
SynonymsCD252;CD134L;OX40Ligand;TNFSF4;TumorNecrosisFactorSuperfamilyMember4;TAXTranscriptionally-activatedGlycoprotein1;TXGP1;gp34
ProductTypeRecombinantAntibody
Properties
CloneR4930
IsotypeHumanIgG1κ
Source/HostCHOcells
Immunogen/AntigenRecombinanthumanOX40L.
Label/ConjugatesPreservativeFree
ApplicationFlowCytometry:1µg/ml
FunctionalApplication(Blocking):Bindstotheco-stimulatoryhumanOX40LinhibitingitsinteractionwithOX40invitroandinvivo.
Optimalconditionsshouldbedeterminedindividuallyforeachapplication.
CrossreactivityHuman
SpecificityRecognizeshumanOX40L.
Purity≥95%(SDS-PAGE)
PurityDetailProteinA-affinitypurified.
EndotoxinContent<0.001eu mu;g="">
Concentration1mg/ml
FormulationLiquid.InPBS.
AccessionNumberUniProtIDP23510
OtherProductDataThisantibodyisabiosimilargenericallycalledOxelumab(CAS1186098-83-8)andoriginallydevelopedbyGenentech.OxelumabisaOX40ligandblockerdesignedforthepreventionofallergen-inducedairwayinflammationinadultswithmildasthma.Potentiallyotherapplicationareasaretransplantationandautoimmunityresearchorprotectionagainstinflammation-drivenfibrosis.
ShippingandHandling
ShippingBLUEICE
ShortTermStorage+4°C
LongTermStorage-20°C
HandlingAdviceAvoidfreeze/thawcycles.
Use/StABIlityStableforatleast1yearafterreceiptwhenstoredat-20°C.
Stableforatleast3monthsafterreceiptwhenstoredat+4°C.
Documents
MSDSDownloadPDF
ProductSpecificationSheet
DatasheetDownloadPDF
OX40L[CD252;CD134L]isamembrane-expressedcytokinethatbelongstotheTNFligandfamily.ItactsascostimulatorthroughinteractionwithitsligandOX40onTcells,stimulatingTcellactivation,proliferationandcytokineproduction.OX40LisexpressedonantigenpresentingcellsincludingBcells,dendriticcells,mastcellsandendothelium.
ProductReferences
  1. InvivoblockadeofOX40ligandinhibitsthymicstromallymphopoietindrivenatopicinflammation:D.Seshasayee,etal.;J.Clin.Invest.117,3868(2007)
  2. Monoclonalantibodiesforthetreatmentofasthma:M.C.Catley,etal.;Pharm.Ther.132,333(2011)
  3. OX40Lblockadeandallergen-inducedairwayresponsesinsubjectswithmildasthma:G.M.Gauvreau,etal.;Clin.Exp.Allergy44,29(2014)
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。