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当前位置: 首页 > 产品中心 > Functional_antibody > Adipogen/anti-Notch2, mAb (16F11) (Biotin)/AG-20B-0052B-C100/100 µg
商品详细Adipogen/anti-Notch2, mAb (16F11) (Biotin)/AG-20B-0052B-C100/100 µg
Adipogen/anti-Notch2, mAb (16F11) (Biotin)/AG-20B-0052B-C100/100 µg
Adipogen/anti-Notch2, mAb (16F11) (Biotin)/AG-20B-0052B-C100/100 µg
商品编号: AG-20B-0052B-C100
品牌: Adipogen Inc
市场价: ¥6200.00
美元价: 3720.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
MoreInformation
ProductDetails
SynonymsNeurogenicLocusNotchHomologProtein2;MotchB
ProductTypeMonoclonalAntibody
Properties
Clone16F11
IsotypeRatIgG1κ
Source/HostPurifiedfromconcentratedhybridomatissueculturesupernatant.
Immunogen/AntigenRecombinantmouseNotch2:Fc(AG-40B-0110).
Label/ConjugatesBiotin
ApplicationFlowCytometry:(1:500)
CrossreactivityHuman
Mouse
SpecificityRecognizeshumanandmouseendogenousNotch2receptor.
Purity≥95%(SDS-PAGE)
PurityDetailProteinG-affinitypurified.
Concentration0.5mg/ml
FormulationLiquid.InPBScontaining0.02%sodiumazide.
ShippingandHandling
ShippingBLUEICE
ShortTermStorage+4°C
LongTermStorage-20°C
HandlingAdviceAfteropening,preparealiquotsandstoreat-20°C.
Avoidfreeze/thawcycles.
Use/StABIlityStableforatleast1yearafterreceiptwhenstoredat-20°C.
Documents
MSDSDownloadPDF
ProductSpecificationSheet
DatasheetDownloadPDF
Notchsignalingpathwayregulatesmanydifferentcellfatedecisionsinbothvertebrateandinvertebratespecies.Thereare5canonicalNotchligandsinmammals:Jagged-1,Jagged-2,DLL1,DLL3andDLL4.ThesecanbindtothefourNotchreceptorsNotch1-4.Itisimportantforpatternformationduringdevelopmentsuchasneurogenesis,angiogenesisormyogenesisandregulatesTcelldevelopmentandstemcellmaintenance.Notchsignalingisalsoinvolvedincellularprocessesthrough-outadulthood.SignalingviaNotchoccursbetweenneighbouringcellsandboththereceptoranditsligandsaretransmembraneproteins.
ProductReferences
  1. DynamicRegulationofNotch1andNotch2SurfaceExpressionduringTCellDevelopmentandActivationRevealedbyNovelMonoclonalAntibodies:E.Fiorini,etal.;J.Immunol.183,7212(2009)
  2. Cuttingedge:ThymicNKcellsdevelopindependentlyfromTcellprecursors:V.S.Ribeiro,etal.;J.Immunol.185,4993(2010)
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。