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Adipogen/anti-NLRP3/NALP3 (mouse), mAb (Cryo-1)/AG-20B-0006-C100/100 µg
Adipogen/anti-NLRP3/NALP3 (mouse), mAb (Cryo-1)/AG-20B-0006-C100/100 µg
商品编号:
AG-20B-0006-C100
品牌:
Adipogen Inc
市场价:
¥7900.00
美元价:
4740.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | NACHT-,LRR-andPYD-containingProtein3;NLRP3;Cryopyrin;ColdAutoinflammatorySyndrome1Protein |
| ProductType | MonoclonalAntibody |
| Properties | |
| Clone | Cryo-1 |
| Isotype | MouseIgG2b |
| Source/Host | Purifiedfromconcentratedhybridomatissueculturesupernatant. |
| Immunogen/Antigen | RecombinantmouseNLRP3/NALP3(pyrindomain/aa1-93). |
| Application | WesternBlot(seeonlineprotocol):(1μg/ml) |
| Crossreactivity | Mouse |
| Specificity | RecognizesmouseNLRP3/NALP3. |
| Purity | ≥95%(SDS-PAGE) |
| PurityDetail | ProteinG-affinitypurified. |
| Concentration | 1mg/ml |
| Formulation | Liquid.InPBScontaining10%glyceroland0.02%sodiumazide. |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Afteropening,preparealiquotsandstoreat-20°C. Avoidfreeze/thawcycles. |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. |
| Documents | |
| Protocols | DownloadPDF |
| MSDS | DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
Theinflammasomeisamultiproteincomplexthatmediatestheactivationofcaspase-1,whichpromotes,amongstothers,thesecretionoftheproinflammatorycytokinesinterleukin(IL)-1βandIL-18.MembersoftheNod-likereceptorfamily,includingNLRP3/NALP3,arecriticalcomponentsoftheinflammasomethatlinkdanger-signalstocaspase-1activation.DefectsinNLRP3arethecauseoffamilialcoldautoinflammatorysyndrometype1(FCAS1),Muckle-Wellssyndrome(MWS)andofchronicinfantileneurologiccutaneousandarticularsyndrome(CINCA).
ProductReferences
- Nlrp6promotesrecoveryafterperipheralnerveinjuryindependentlyofinflammasomes:E.Ydens,etal.;J.Neuroinfl.12,143(2015)
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。
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