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Adipogen/anti-Jagged-1 (human), mAb (J1G53-3) (FITC)/AG-20A-0049F-C050/50 µg
Adipogen/anti-Jagged-1 (human), mAb (J1G53-3) (FITC)/AG-20A-0049F-C050/50 µg
商品编号：
AG-20A-0049F-C050
品牌：
Adipogen Inc
市场价：
¥4800.00
美元价：
2880.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Details | |
|---|---|
| Synonyms | Protein Jagged-1; CD339; JAG1 |
| Product Type | Monoclonal Antibody |
| Properties | |
| Clone | J1G53-3 |
| Isotype | Mouse IgG1κ |
| Immunogen/Antigen | Recombinant human Jagged-1. |
| Label/Conjugates | FITC |
| Application |
Flow Cytometry: (1:20-1:100) Western blot: (1:500-1:5'000 using ECL. Suggested blocking and dilution buffer is PBST with 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at rooom temperature). Optimal conditions should be determined individually for each application. |
| Crossreactivity | Human |
| Specificity | Recognizes human Jagged-1. Detects a band of ~180kDa by Western blot. |
| Purity Detail | Protein G-affinity purified. |
| Concentration | 1mg/ml |
| Formulation | Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Jagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It is involved in cell-fate decisions during hematopoiesis. Is involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro). Defects in Jagged-1 are the cause of Alagille syndrome type 1 (ALGS1) and tetralogy of Fallot (TOF).
Product References
- Preclinical activity of the repurposed drug auranofin in classical Hodgkin lymphoma: M. Celegato, et al., Blood 126, 1394 (2015)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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