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Adipogen/anti-Irisin, pAb (IN102) (Biotin)/AG-25B-0027B-C100/100 µg
Adipogen/anti-Irisin, pAb (IN102) (Biotin)/AG-25B-0027B-C100/100 µg
商品编号：
AG-25B-0027B-C100
品牌：
Adipogen Inc
市场价：
¥7900.00
美元价：
4740.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Details | |
|---|---|
| Synonyms | Fibronectin Type III Domain-containing Protein 5 (cleaved); Fibronectin Type III Repeat-containing Protein 2 (cleaved); FNDC5 (cleaved) |
| Product Type | Polyclonal Antibody |
| Properties | |
| Source/Host | Rabbit |
| Immunogen/Antigen | Recombinant irisin. |
| Label/Conjugates | Biotin |
| Application |
Western Blot: (1:1'000) ELISA:(Detection) |
| Crossreactivity |
Human Monkey Mouse Rat |
| Specificity | Recognizes human, mouse, rat, monkey Irisin and FNDC5. Detects endogenous mouse and human Irisin [Lit: 1-2]. |
| Purity Detail | Protein A-affinity purified. |
| Concentration | 0.5 mg /ml |
| Formulation | Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone Irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure.
Product References
- Exercise Induces Hippocampal BDNF through a PGC-1α/FNDC5 Pathway: C.D. Wrann, et al.; Cell Metab. 18, 649 (2013)
- Detection and quantitation of circulating human irisin by tandem mass spectrometry: M.P. Jedrychowski, et al.; Cell Metab. 22, 734 (2015)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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