Adipogen/anti-IL-33 (mouse), pAb/AG-25A-0047-C100/100 µg
商品编号：
AG-25A-0047-C100
品牌：
Adipogen Inc
市场价：
¥5800.00
美元价：
3480.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | Interleukin-33;IL-1F11;NF-HEV |
| ProductType | PolyclonalAntibody |
| Properties | |
| Source/Host | Rabbit |
| Immunogen/Antigen | RecombinantmouseIL-33. |
| Application | ELISA:(directandindirect:1:2’000-1:5’000) WesternBlot:(1:2’000-1:5’000usingECL;suggestedblockinganddilutionbufferisPBSTcontaining0.05%Tween20and5%skimmilk;suggestedincubationtimeis1houratroomtemperature). Optimalconditionsmustbedeterminedindividuallyforeachapplication. |
| Crossreactivity | Mouse |
| Specificity | RecognizesmouseIL-33.Detectsabandof~18kDabyWesternblot.Doesnotcross-reactwithhumanIL-33. |
| PurityDetail | ProteinA-affinitypurified. |
| Concentration | 1mg/ml |
| Formulation | Liquid.0.2μm-filteredsolutioninPBS,pH7.4.Containsnopreservatives. |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Afteropening,preparealiquotsandstoreat-20°C. Avoidfreeze/thawcycles. |
| Use/StABIlity | Stableforatleast6monthsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
Interleukin-33(IL-33;HF-NEV;IL-1F11),amemberoftheIL-1familyofcytokines,isexpressedbymanycelltypesfollowingpro-inflammatorystimulationandisthoughttobereleasedoncelllysis.The30kDahumanIL33isconvertedbyCASP1toa18kDaprotein.IL33bindstoandsignalsthroughST2(IL1R1)anditsstimulationrecruitsMYD88,IRAK,IRAK4,andTRAF6,followedbyphosphorylationofERK1(MAPK3)/ERK2(MAPK1),p38(MAPK14),andJNK.TheabilityofIL-33totargetnumerousimmunecelltypes,likeTh2-likecells,mastcells,andB1cells,andtoinducecytokineandchemokineproductionunderlinesitspotentialininfluencingtheoutcomeofawiderangeofdiseases,suchasarthritis,asthma,atopicallergy&anaphylaxis,cardiovasculardisease/atherosclerosis,nervoussystemdiseases,andsepsis.
ProductReferences
- SolubleST2blocksinterleukin-33signalinginallergicairwayinflammation:H.Hayakawa,etal.;JBC282,26369(2007)
- Anovelmethodforprocuringalargequantityofmaturemurineeosinophilsinvivo:W.Kim,etal.;J.Immunol.Methods363,90(2010)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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