4000-520-616
欢迎来到免疫在线!(蚂蚁淘生物旗下平台)  请登录 |  免费注册 |  询价篮
主营:主营:癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域
咨询热线电话
4000-520-616
当前位置: 首页 > 产品中心 > Functional_antibody > Adipogen/anti-Hexanoyl-Lys [HEL], mAb (5F12)/JAI-MHL-021P/20 µg
商品详细Adipogen/anti-Hexanoyl-Lys [HEL], mAb (5F12)/JAI-MHL-021P/20 µg
Adipogen/anti-Hexanoyl-Lys [HEL], mAb (5F12)/JAI-MHL-021P/20 µg
Adipogen/anti-Hexanoyl-Lys [HEL], mAb (5F12)/JAI-MHL-021P/20 µg
商品编号: JAI-MHL-021P
品牌: Adipogen Inc
市场价: ¥3480.00
美元价: 2088.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
MoreInformation
ProductDetails
ProductTypeMonoclonalAntibody
Properties
Clone5F12
IsotypeMouseIgG1κ
Immunogen/AntigenNepsilonhexanoyl-keyholelimpethemocyanin(HEL-KLH).
ApplicationELISA
Immunohistochemistry:Recommendedconcentrationis2μg/mLonparaffinsections.
WesternBlot
CrossreactivityAll
Human
SpecificityRecognizesHexanoyl-Lysadducts.Doesnotcross-reactwithMDA,glyoxal,methylglyoxal,1-hexanal,2-hexenal,1-nonannal,2-nonenal,4-hudroxy-2-nonenal.
FormulationLyophilized.Contains10mMPBS(pH7.4),5%sucrose,1%BSAand0.05%Procline950.
ReconstitutionReconstitutewith200μLdistilledwater.
OtherProductDataClickhereforOriginalManufacturerProductDatasheet
Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet.
DeclarationManufacturedbyJaICA.
ShippingandHandling
ShippingBLUEICE
ShortTermStorage+4°C
LongTermStorage-20°C
HandlingAdviceAvoidfreeze/thawcycles.
Use/StABIlityStableforatleast3yearsafterreceiptwhenstoredat-20°C.
Afterreconstitution,preparealiquotsandstoreat-20°C.
Documents
ProtocolsDownloadPDF
MSDSNo
ProductSpecificationSheet
DatasheetDownloadPDF
Oxidativedamagetolipids(lipidperoxidation)hasbeenfoundtoplayanimportantroleinvariousdiseaseandagingprocesses.Duringearlystagesoflipidperoxidation,lipidhydroperoxides(LOOH)areformed.Thesecanreactadditionallytoformlaterstageendproductssuchasmalondialdehyde(MDA)andhydroxynonenal(HNE).LOOHismeasuredtoquantifyearlystageoracutelipidperoxidationwhileMDAiscommonlymeasuredtoquantifylatestageorchroniclipidperoxidation.Morerecently,ithasbeenreportedthat13-hydroperoxyoctadecanoicacid(13-HPODE),aprecursorto13-hydroxyoctadecanoicacid(13-HODE)canreactwithproteinstoformmeasurableadductsbycovalentlybindingtospecificaminoacidresidues.TheHexanoyl-Lysine(HEL)adductisformeduponoxidativemodificationofomega-6fattyacidssuchaslinoleicacid,thepredominantpolyunsaturatedfattyacid(PUFA)inthehumandiet,andarachidonicacid.HELmaybeanotherusefulbioMarkerfordetectingandquantifyingtheearlierstagesoflipidperoxidation.
ProductReferences
  1. PreparationofamonoclonalantibodytoN(epsilon)-(Hexanonyl)lysine:applicationtotheevaluationofprotectiveeffectsofflavonoidsupplementationagainstexercise-inducedoxidativestressinratskeletalmuscle:Y.Kato,etal.;BBRC274,389(2000)[Developmentandcharacterizationofanti-HELmonoclonalantibody]
  2. Immunohistochemicaldetectionofoxidativestressbiomarkers,dityrosineandN(epsilon)-(hexanoyl)lysine,andC-reactiveproteininrabbitatheroscleroticlesions:Y.Fukuchi,etal.;J.Atheroscler.Thromb.15,185(2008)[Applicationtorabbitatheroscleroticlesions]
  3. Awater-solublefullerenevesiclealleviatesangiotensinII-inducedoxidativestressinhumanumbilicalvenousendothelialcells:R.Maeda,etal.;Hypertens.Res.31,141(2008)[Applicationtoculturedcells(HUVECs)]
  4. DifferentialEffectsofHighGlucoseandMethylglyoxalonViabilityandPolyolMetabolisminImmortalizedAdultMouseSchwannCells:K.Sango,etal.;OpenDiabetesJ.1,1(2008)[Applicationtoculturedcellfrommouse]
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。