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Adipogen/anti-Hexanoyl-Lys [HEL], mAb (5F12)/JAI-MHL-021P/20 µg
Adipogen/anti-Hexanoyl-Lys [HEL], mAb (5F12)/JAI-MHL-021P/20 µg
商品编号:
JAI-MHL-021P
品牌:
Adipogen Inc
市场价:
¥3480.00
美元价:
2088.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| ProductType | MonoclonalAntibody |
| Properties | |
| Clone | 5F12 |
| Isotype | MouseIgG1κ |
| Immunogen/Antigen | Nepsilonhexanoyl-keyholelimpethemocyanin(HEL-KLH). |
| Application | ELISA Immunohistochemistry:Recommendedconcentrationis2μg/mLonparaffinsections. WesternBlot |
| Crossreactivity | All Human |
| Specificity | RecognizesHexanoyl-Lysadducts.Doesnotcross-reactwithMDA,glyoxal,methylglyoxal,1-hexanal,2-hexenal,1-nonannal,2-nonenal,4-hudroxy-2-nonenal. |
| Formulation | Lyophilized.Contains10mMPBS(pH7.4),5%sucrose,1%BSAand0.05%Procline950. |
| Reconstitution | Reconstitutewith200μLdistilledwater. |
| OtherProductData | ClickhereforOriginalManufacturerProductDatasheet Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet. |
| Declaration | ManufacturedbyJaICA. |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Avoidfreeze/thawcycles. |
| Use/StABIlity | Stableforatleast3yearsafterreceiptwhenstoredat-20°C. Afterreconstitution,preparealiquotsandstoreat-20°C. |
| Documents | |
| Protocols | DownloadPDF |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
Oxidativedamagetolipids(lipidperoxidation)hasbeenfoundtoplayanimportantroleinvariousdiseaseandagingprocesses.Duringearlystagesoflipidperoxidation,lipidhydroperoxides(LOOH)areformed.Thesecanreactadditionallytoformlaterstageendproductssuchasmalondialdehyde(MDA)andhydroxynonenal(HNE).LOOHismeasuredtoquantifyearlystageoracutelipidperoxidationwhileMDAiscommonlymeasuredtoquantifylatestageorchroniclipidperoxidation.Morerecently,ithasbeenreportedthat13-hydroperoxyoctadecanoicacid(13-HPODE),aprecursorto13-hydroxyoctadecanoicacid(13-HODE)canreactwithproteinstoformmeasurableadductsbycovalentlybindingtospecificaminoacidresidues.TheHexanoyl-Lysine(HEL)adductisformeduponoxidativemodificationofomega-6fattyacidssuchaslinoleicacid,thepredominantpolyunsaturatedfattyacid(PUFA)inthehumandiet,andarachidonicacid.HELmaybeanotherusefulbioMarkerfordetectingandquantifyingtheearlierstagesoflipidperoxidation.
ProductReferences
- PreparationofamonoclonalantibodytoN(epsilon)-(Hexanonyl)lysine:applicationtotheevaluationofprotectiveeffectsofflavonoidsupplementationagainstexercise-inducedoxidativestressinratskeletalmuscle:Y.Kato,etal.;BBRC274,389(2000)[Developmentandcharacterizationofanti-HELmonoclonalantibody]
- Immunohistochemicaldetectionofoxidativestressbiomarkers,dityrosineandN(epsilon)-(hexanoyl)lysine,andC-reactiveproteininrabbitatheroscleroticlesions:Y.Fukuchi,etal.;J.Atheroscler.Thromb.15,185(2008)[Applicationtorabbitatheroscleroticlesions]
- Awater-solublefullerenevesiclealleviatesangiotensinII-inducedoxidativestressinhumanumbilicalvenousendothelialcells:R.Maeda,etal.;Hypertens.Res.31,141(2008)[Applicationtoculturedcells(HUVECs)]
- DifferentialEffectsofHighGlucoseandMethylglyoxalonViabilityandPolyolMetabolisminImmortalizedAdultMouseSchwannCells:K.Sango,etal.;OpenDiabetesJ.1,1(2008)[Applicationtoculturedcellfrommouse]
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。
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