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Adipogen/anti-GPx8 (human), pAb (IN103)/AG-25B-0028-C100/100 µg
Adipogen/anti-GPx8 (human), pAb (IN103)/AG-25B-0028-C100/100 µg
商品编号:
AG-25B-0028-C100
品牌:
Adipogen Inc
市场价:
¥7000.00
美元价:
4200.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | ProbableGlutathionePeroxidase8;GSHPx-8 |
| ProductType | PolyclonalAntibody |
| Properties | |
| Source/Host | Rabbit |
| Immunogen/Antigen | RecombinantGPx8(human)(aa38-209)fusedtoaGST-tag. |
| Application | WesternBlot:(1:1"000) ICC:(1:200) |
| Crossreactivity | HCV |
| Specificity | RecognizeshumanGPx8. |
| PurityDetail | Protein-Aaffinitypurified. |
| Concentration | 1mg/ml |
| Formulation | Liquid.InPBScontaining10%glyceroland0.02%sodiumazide. |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Afteropening,preparealiquotsandstoreat-20°C. Avoidfreeze/thawcycles. |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS | DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
GPxsareglutathioneperoxidasesinvolvedinbalancingtheH2O2homeostasisinsignalingcascades.GPxshavebeenknowntocatalyzethereductionofH2O2ororganichydroperoxidestowaterorthecorrespondingalcohols,respectively,typicallyusingglutathione(GSH)asreductant.GPx8(probableglutathioneperoxidase8)isa209-aa,24kDaproteinwithanN-terminalcytosolictip,apredictedtransmembranesegmentandacatalyticdomainlocatedintheendoplasmicreticulum(ER)lumen.GPx8isaCysGPxswithlowglutathioneperoxidaseactivity.ArecentstudyidentifiedGPx8asacellularsubstrateofthehepatitisCvirusNS3-4Aprotease.GPx8cleavagebyNS3-4AoccursatCys11,removingthecytosolictipofGPx8andwasobservedindifferentexperimentalsystemsaswellasinliverbiopsiesfrompatientswithchronichepatitisC.
ProductReferences
- Quantitativeproteomicsidentifiesthemembrane-associatedperoxidaseGPx8asacellularsubstrateofthehepatitisCvirusNS3-4Aprotease:K.Morikawa,etal.;Hepatology59,423(2014)
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。
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